Results 211 to 220 of about 45,688,233 (408)

Long‐term effect of caesarean section on the gut microbial taxonomical profile and metabolic function of children at pre‐school age

Clinical and Translational Medicine, 2023
Chang Gao, Dan‐Tong Shao, Cheng‐Rui Wang, Ya‐Shu Kuang, Jin‐Hua Lu, Ding‐Yuan Zeng, Jian‐Rong He, Xiu Qiu   +7 more
doaj   +1 more source

The Millennium Cohort Study.

Population trends, 2002
The Millennium Cohort Study is the latest in the line of British birth cohort studies. MCS resembles its predecessors which follow people born in 1946, 1958 and 1970 in the intention to become multi-purpose longitudinal data resource charting many aspects of individual's lives over time.
Smith, K, Joshi, H
openaire   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Combining longitudinal cohort studies to examine cardiovascular risk factor trajectories across the adult lifespan [PDF]

arXiv
We introduce a statistical framework for combining data from multiple large longitudinal cardiovascular cohorts to enable the study of long-term cardiovascular health starting in early adulthood. Using data from seven cohorts belonging to the Lifetime Risk Pooling Project (LRPP), we present a Bayesian hierarchical multivariate approach that jointly ...
arxiv  

Female gender is associated with long COVID syndrome: a prospective cohort study

Clinical Microbiology and Infection, 2021
F. Bai, Daniele Tomasoni, Camilla Falcinella, D. Barbanotti, Roberto Castoldi, G. Mulé, M. Augello, D. Mondatore, M. Allegrini, A. Cona, D. Tesoro, G. Tagliaferri, Ottavia Viganò, E. Suardi, C. Tincati, Tomaso Beringheli, Benedetta Varisco, C. Battistini, Kyrie Piscopo, E. Vegni, A. Tavelli, S. Terzoni, G. Marchetti, A. Monforte   +23 more
semanticscholar   +1 more source

Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. [PDF]

, 2016
This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitalized with an ...
Armstrong, Jon, Arrieta, Antonio, Bishai, Raafat, Bradley, John S, Das, Shampa, Delair, Shirley, Edeki, Timi, Holmes, William C, Li, Jianguo, Moffett, Kathryn S, Mukundan, Deepa, Perez, Norma, Romero, José R, Speicher, David, Sullivan, Janice E, Zhou, Diansong   +15 more
core  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Similarity-Informed Transfer Learning for Multivariate Functional Censored Quantile Regression [PDF]

arXiv
To address the challenge of utilizing patient data from other organ transplant centers (source cohorts) to improve survival time estimation and inference for a target center (target cohort) with limited samples and strict data-sharing privacy constraints, we propose the Similarity-Informed Transfer Learning (SITL) method.
arxiv  

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

The value of fetal growth trajectory during pregnancy in predicting small for gestational age neonates at term

BMC Pregnancy and Childbirth
Background The predictive value of trajectory identified by group-based trajectory modeling (GBTM) has been discussed but its value in predicting small for gestational age (SGA) neonates is still unclear.
Huimin Zhu, Min Wei, Xiuxiu Li, Xuemei Liu, Jin Li, Xuemei Fan, Zhen Wang, Weiqing Chen   +7 more
doaj   +1 more source