Results 221 to 230 of about 45,688,233 (408)

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Progestogen use and decreased risk of breast cancer in a cohort study of premenopausal women with benign breast disease [PDF]

open access: green, 1994
Geneviève Plu‐Bureau   +4 more
openalex   +1 more source

COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study

open access: yesThe Lancet Child & Adolescent Health, 2020
Florian Götzinger   +115 more
semanticscholar   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Cohort Profile: The Swiss HIV Cohort Study [PDF]

open access: yesInternational Journal of Epidemiology, 2009
Swiss HIV Cohort Study,   +9 more
openaire   +4 more sources

Harnessing Increased Client Participation with Cohort-Parallel Federated Learning [PDF]

open access: yesarXiv
Federated learning (FL) is a machine learning approach where nodes collaboratively train a global model. As more nodes participate in a round of FL, the effectiveness of individual model updates by nodes also diminishes. In this study, we increase the effectiveness of client updates by dividing the network into smaller partitions, or cohorts.
arxiv  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy