Results 131 to 140 of about 64,848 (301)
Advanced Science, EarlyView.An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang +8 more
wiley +1 more source
The fate of one-dollar coins in the U.S. [PDF]
The United States has introduced two one-dollar coins in the past 25 years, both of which have not circulated widely. Many other countries have replaced lower-denomination notes with coins and have achieved wide circulation and cost savings. Lessons from
Guillaume Rocheteau, Sébastien Lotz
core
Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement
Advanced Science, EarlyView.The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang +7 more
wiley +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Advanced Science, EarlyView.Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source
Avoiding a meltdown: managing the value of small change [PDF]
To prevent a shortage of small change, the U.S. Department of the Treasury recently prohibited the melting and exportation of pennies and other coins.
François R. Velde
core
Lithiophilic Current Collector Without Interfacial Penalty in Zero‐Excess Lithium Metal Batteries
Advanced Science, EarlyView.Bilayer lithiophilic coatings are introduced to overcome the structural fragility of conventional single‐layer current collectors in zero‐excess Li‐metal batteries (ZE‐LMBs). By integrating density functional theory with electrochemical analyses, the Ag‐outer/Pt‐inner configuration enables uniform Li deposition, robust SEI formation, and persistent ...
Jiyeon Seo +8 more
wiley +1 more source
Advanced Science, EarlyView.Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Money, prices, wages, and ‘profit inflation’ in Spain, the Southern Netherlands, and England during the Price Revolution era, ca. 1520 - ca. 1650 [PDF]
This article re-examines Earl Hamilton’s famous 1929 thesis on ‘Profit Inflation’ and the ‘birth of modern industrial capitalism’: namely, that the inflationary forces of the Price Revolution era produced a widening gap between prices and wages, thus ...
Munro, John H.
core +1 more source
Advanced Science, EarlyView.Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul +12 more
wiley +1 more source
Money on the Road to Empire —Japan's Choice for Gold Monometallism [PDF]
Matsukata Masayoshi's decision to bring Japan upon the gold standard has often been presented as the self-evident result of his insight in some imperfections endemic to the silver standard and bimetallism.
Schiltz, Michael
core +1 more source