Results 101 to 110 of about 706,018 (368)

Physiology of Layer 5 Pyramidal Neurons in Mouse Primary Visual Cortex: Coincidence Detection through Bursting

open access: yesPLoS Comput. Biol., 2015
L5 pyramidal neurons are the only neocortical cell type with dendrites reaching all six layers of cortex, casting them as one of the main integrators in the cortical column.
A. Shai   +3 more
semanticscholar   +1 more source

​Did a Non‐Medical Biosimilar Switching Policy Cause an Increase in Non‐Biologic/Biosimilar Health Care Resource Utilization or Cost in Patients With Inflammatory Arthritis?

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the impact of a series of policies that mandated switching patients with inflammatory arthritis (IA) from an originator biologic to a biosimilar in British Columbia, Canada, on health care resource use and cost.
HaoHung Dang   +4 more
wiley   +1 more source

A new anti-neutrino detection technique based on positronium tagging with plastic scintillators

open access: yes, 2015
The main signature for anti-neutrino detection in reactor and geo-neutrino experiments based on scintillators is provided by the space-time coincidence of positron and neutron produced in the Inverse Beta Decay reaction.
Consolati, G.   +6 more
core   +3 more sources

In vivo coincidence detection in mammalian sound localization generates phase delays

open access: yesNature Neuroscience, 2015
Sound localization critically depends on detection of differences in arrival time of sounds at the two ears (acoustic delay). The fundamental mechanisms are debated, but all proposals include a process of coincidence detection and a separate source of ...
Tom P. Franken   +4 more
semanticscholar   +1 more source

Assessment of skin in patients with systemic sclerosis using high‐frequency ultrasound and shear wave elastography: A comparative study with histology, molecular and clinical parameters

open access: yesArthritis Care &Research, Accepted Article.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histological markers of skin fibrosis has not been reported. We evaluated the US‐based skin assessments for their face validity (differentiation between involved SSc and ...
Ruhani Desai   +12 more
wiley   +1 more source

Mutation incidence and coincidence in non small-cell lung cancer: meta-analyses by ethnicity and histology (mutMap)

open access: yesAnnals of Oncology, 2013
Background Meta-analyses were conducted to characterize patterns of mutation incidence in non small-cell lung cancer (NSCLC). Design Nine genes with the most complete published mutation coincidence data were evaluated.
S. Dearden   +3 more
semanticscholar   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Nonstabilized Nielsen coincidence invariants and Hopf--Ganea homomorphisms

open access: yes, 2006
In classical fixed point and coincidence theory the notion of Nielsen numbers has proved to be extremely fruitful. We extend it to pairs (f_1,f_2) of maps between manifolds of arbitrary dimensions, using nonstabilized normal bordism theory as our main ...
Bogatyĭ   +13 more
core   +3 more sources

Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro

open access: yesAdvanced Biology, EarlyView.
Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi   +10 more
wiley   +1 more source

SU(3) Quantum Interferometry with single-photon input pulses

open access: yes, 2013
We develop a framework for solving the action of a three-channel passive optical interferometer on single-photon pulse inputs to each channel using SU(3) group-theoretic methods, which can be readily generalized to higher-order photon-coincidence ...
Barry C. Sanders   +5 more
core   +1 more source

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