Results 61 to 70 of about 603,566 (315)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Coincidence theory for compact morphisms
In this paper we present several coincidence type results for morphisms (fractions) in the sense of Gorniewicz and Granas.
Donal O’Regan
doaj +1 more source
Multimessenger Gamma-Ray and Neutrino Coincidence Alerts Using HAWC and IceCube Subthreshold Data [PDF]
H. A. Ayala Solares +99 more
openalex +1 more source
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Roles for Coincidence Detection in Coding Amplitude-Modulated Sounds. [PDF]
Many sensory neurons encode temporal information by detecting coincident arrivals of synaptic inputs. In the mammalian auditory brainstem, binaural neurons of the medial superior olive (MSO) are known to act as coincidence detectors, whereas in the ...
Go Ashida +2 more
doaj +1 more source
Dark-Energy Dynamics Required to Solve the Cosmic Coincidence
Dynamic dark energy (DDE) models are often designed to solve the cosmic coincidence (why, just now, is the dark energy density $\rho_{de}$, the same order of magnitude as the matter density $\rho_m$?) by guaranteeing $\rho_{de} \sim \rho_m$ for ...
B. Carter +7 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
In this article, we study the self-adjoint second-order boundary-value problem with integral boundary conditions, $$displaylines{ (p(t)x'(t))'+ f(t,x(t))=0,quad tin (0,1),cr p(0)x'(0)=p(1)x'(1),quad x(1)=int_0^1x(s)g(s)ds, }$$ which involves an ...
Aijun Yang, Bo Sun, Weigao Ge
doaj
Lightning discharge identification system [PDF]
A system for differentiating between cloud to cloud and cloud to ground lightning discharges is described which includes an electric field antenna that senses the rate of charge of an electric field produced by a lightning discharge.
Lennon, C. L.
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source

