Results 71 to 80 of about 700,986 (323)

Dissociative photoionization of the NO molecule studied by photoelectron-photon coincidence technique

open access: yes, 2010
Low-energy photoelectron–vacuum ultraviolet (VUV) photon coincidences have been measured using synchrotron radiation excitation in the inner-valence region of the nitric oxide molecule.
A. Kivimäki   +42 more
core   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

The Rationale of Crisis Management – On the Handling of Coincidence in Economic Situation [PDF]

open access: yesJournal of Social Science Education, 2010
The subject of this essay is too complex a problem as to cover all details in depth and, thus, draws its attention only to core aspects of the handling of coincidence leaving out sophisticated studies and analytic findings as well as detailed reference ...
Peter Bendixen
doaj  

Dark-Energy Dynamics Required to Solve the Cosmic Coincidence

open access: yes, 2008
Dynamic dark energy (DDE) models are often designed to solve the cosmic coincidence (why, just now, is the dark energy density $\rho_{de}$, the same order of magnitude as the matter density $\rho_m$?) by guaranteeing $\rho_{de} \sim \rho_m$ for ...
B. Carter   +7 more
core   +1 more source

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler   +43 more
wiley   +1 more source

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague   +8 more
wiley   +1 more source

Coincidence theory for compact morphisms

open access: yesFixed Point Theory and Applications, 2017
In this paper we present several coincidence type results for morphisms (fractions) in the sense of Gorniewicz and Granas.
Donal O’Regan
doaj   +1 more source

Geometric and homotopy theoretic methods in Nielsen coincidence theory

open access: yes, 2006
In classical fixed point and coincidence theory the notion of Nielsen numbers has proved to be extremely fruitful. Here we extend it to pairs (f_1, f_2) of maps between manifolds of arbitrary dimensions. This leads to estimates of the minimum numbers MCC(
Koschorke, Ulrich
core   +4 more sources

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann   +6 more
wiley   +1 more source

​Did a Non‐Medical Biosimilar Switching Policy Cause an Increase in Non‐Biologic/Biosimilar Health Care Resource Utilization or Cost in Patients With Inflammatory Arthritis?

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the impact of a series of policies that mandated switching patients with inflammatory arthritis (IA) from an originator biologic to a biosimilar in British Columbia, Canada, on health care resource use and cost.
HaoHung Dang   +4 more
wiley   +1 more source

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