Results 51 to 60 of about 4,588,868 (289)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Some Coincidence and Common Fixed Point Results in Fuzzy Metric Space with an Application to Differential Equations

open access: yesJournal of Function Spaces, 2021
In this paper, we study some coincidence point and common fixed point theorems in fuzzy metric spaces by using three-self-mappings. We prove the uniqueness of some coincidence point and common fixed point results by using the weak compatibility of three ...
Saif Ur Rehman   +4 more
doaj   +1 more source

Some results on coincidence points [PDF]

open access: yesBulletin of the Australian Mathematical Society, 1999
In this paper we prove some coincidence point theorems for nonself single-valued and multivalued maps satisfying a nonexpansive condition. These extend fixed point theorems for multivalued maps of a number of authors.
Latif, Abdul, Tweddle, Ian
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Central Point Notice of Adopted Amendment (2012-06-04) [PDF]

open access: yes, 2012
46 pp. Adopted 2012-06-04. Department of Land Conservation and Development Notice of Adopted AmendmentComprehensive Plan Map (Exhibit 1) and concurrent Zone Map (Exhibit 2 change for 7.61 acres within the UGE of Central Point from Neighborhood ...
Myrtle Point (Or.), Central Point (Or.)
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Fixed Point Theorems, Coincidence Point Theorems and Their Applications [PDF]

open access: yes, 2016
This study aims to illuminate a general framework for fixed point and coincidence point theorems. Our theorems work with functions defined on ball spaces (X,\cB).
Sonaallah, Fatma 1986-
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Annual report 2001/2002 - Pavee Point [PDF]

open access: yes, 2003
Pavee Point ...
Pavee Point Travellers Centre
core  

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