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ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
In this paper, we study some coincidence point and common fixed point theorems in fuzzy metric spaces by using three-self-mappings. We prove the uniqueness of some coincidence point and common fixed point results by using the weak compatibility of three ...
Saif Ur Rehman +4 more
doaj +1 more source
Some results on coincidence points [PDF]
In this paper we prove some coincidence point theorems for nonself single-valued and multivalued maps satisfying a nonexpansive condition. These extend fixed point theorems for multivalued maps of a number of authors.
Latif, Abdul, Tweddle, Ian
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Central Point Notice of Adopted Amendment (2012-06-04) [PDF]
46 pp. Adopted 2012-06-04. Department of Land Conservation and Development Notice of Adopted AmendmentComprehensive Plan Map (Exhibit 1) and concurrent Zone Map (Exhibit 2 change for 7.61 acres within the UGE of Central Point from Neighborhood ...
Myrtle Point (Or.), Central Point (Or.)
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Fixed Point Theorems, Coincidence Point Theorems and Their Applications [PDF]
This study aims to illuminate a general framework for fixed point and coincidence point theorems. Our theorems work with functions defined on ball spaces (X,\cB).
Sonaallah, Fatma 1986-
core
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

