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Australasian Annals of Medicine, 1968
SUMMARYA case of self‐administered overdosage of colchicine is described. Despite gastrointestinal, hærnopoietic, neurological, hepatic and renal damage, together with alopecia, stomatitis, fever,transient hypertension and arthralgia, the patient survived.This wide range of toxic effects has been recorded in animal experiments, but seldom occurs in ...
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SUMMARYA case of self‐administered overdosage of colchicine is described. Despite gastrointestinal, hærnopoietic, neurological, hepatic and renal damage, together with alopecia, stomatitis, fever,transient hypertension and arthralgia, the patient survived.This wide range of toxic effects has been recorded in animal experiments, but seldom occurs in ...
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Colchicine for the Treatment of Pericarditis
Future Cardiology, 2008Colchicine has been effectively used in the treatment of several inflammatory conditions, such as gouty attacks, serositis related to familial Mediterranean fever, Behçet syndrome and more recently, in acute and recurrent pericarditis. Colchicine concentrates in white blood cells, particularly polymorphonuclear cells, inhibiting tubulin polymerization,
Massimo Imazio +2 more
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Cardiotoxicity of colchicine in the rat
Intensive Care Medicine, 1994Colchicine poisoning may be lethal and a decrease in cardiac function has been reported in several case reports, but the precise cardiotoxicity of colchicine remains unknown.The experimental in vitro study assessed the intrinsic contractility of left ventricular papillary muscle in rats, 24 h after administration of intraperitoneal colchicine or saline.
P Mery +4 more
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