Results 171 to 180 of about 187,838 (300)

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Lewis Pair-Engineered CuMnO_x as Cold-Adapted Multinanozyme for Cooperative Hydrolytic and Oxidative Degradation of Raw Corn Stalk. [PDF]

Adv Sci (Weinh)
Liu H, Di Z, Tian Q, Zhou Y, Yang R, Bai Z, Wang H, Chen Y, Zhang L.   +8 more
europepmc   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Comparison of efficacy, safety, immune response of dNS1 LAIV and cold-adapted LAIV in a mouse model. [PDF]

NPJ Vaccines
Wang X, Zhang X, Chen C, Chen H, Chen Y, Wu R, Chen X, Lu Z, Xia N, Chen J, Chen Y.   +10 more
europepmc   +1 more source

Metabolic Robustness to Growth Temperature of a Cold- Adapted Marine Bacterium. [PDF]

mSystems, 2023
Riccardi C, Calvanese M, Ghini V, Alonso-Vásquez T, Perrin E, Turano P, Giurato G, Weisz A, Parrilli E, Tutino ML, Fondi M.   +10 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Catalytically active inclusion bodies of cold-adapted lipase: production and its industrial potential. [PDF]

AMB Express
Bello MN, Sabri S, Yahaya NM, Shariff FM, Mohamad Ali MS.   +4 more
europepmc   +1 more source

The genus Rachicladosporium: introducing new species from sooty mould communities and excluding cold adapted species. [PDF]

Sci Rep, 2023
Piątek M, Stryjak-Bogacka M, Czachura P, Owczarek-Kościelniak M.   +3 more
europepmc   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Chemoautotrophy in subzero environments and the potential for cold-adapted Rubisco. [PDF]

Appl Environ Microbiol
Harrison K, Rapp JZ, Jaffe AL, Deming JW, Young J.   +4 more
europepmc   +1 more source