Results 251 to 260 of about 187,838 (300)
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Cold-adapted influenza vaccines
Current Opinion in Pediatrics, 2002Because of the health impact of complicated disease from influenza in children, the role played by children in spreading influenza, and the limitations of inactivated influenza vaccine in this population, there has been ongoing effort to identify a more effective and acceptable vaccine.
John, Bradshaw, Peter F, Wright
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Cold Adaptation of Tropomyosin
Biochemistry, 2011The conformational stability of unphosphorylated and phosphorylated α,α-striated tropomyosins from rabbit and shark (95% identical sequences) has been investigated. Three additional core positions are occupied by atypical amino acids in the protein from shark: Thr179(d), Ser190(a), and Ser211(a).
Michael, Hayley +2 more
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2000
The number of reports on enzymes from cold adapted organisms has increased significantly over the past years, and reveals that adaptive strategies for functioning at low temperature varies among enzymes. However, the high catalytic efficiency at low temperature seems, for the majority of cold active enzymes, to be accompanied by a reduced thermal ...
A O, Smalås +3 more
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The number of reports on enzymes from cold adapted organisms has increased significantly over the past years, and reveals that adaptive strategies for functioning at low temperature varies among enzymes. However, the high catalytic efficiency at low temperature seems, for the majority of cold active enzymes, to be accompanied by a reduced thermal ...
A O, Smalås +3 more
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Cold-adapted Euplotes Pheromones
European Journal of Protistology, 2003Species of Euplotes rely on diffusible signal proteins (pheromones) to promote their mitotic reproduction and mating (sexual) phenomena. Two of these pheromones have recently been structurally characterized from an Antarctic species, E. nobilii, and their amino acid sequences (of 52 and 60 residues, and eight cysteines) were found to be closely related
C. ALIMENTI +3 more
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Trends in Biotechnology, 1997
It is an article of faith among biochemists and molecular biologists that precious enzymes must be stored on ice. The usual reason given is that, at temperatures around freezing, enzyme activity is minimized and protein stability maximized. There is considerable evidence supporting this, but is it true for all enzymes? What about enzymes from organisms
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It is an article of faith among biochemists and molecular biologists that precious enzymes must be stored on ice. The usual reason given is that, at temperatures around freezing, enzyme activity is minimized and protein stability maximized. There is considerable evidence supporting this, but is it true for all enzymes? What about enzymes from organisms
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Cold-adaptation of human rotavirus
Virus Research, 1987A human rotavirus strain was cold-adapted for possible future use as a live vaccine. The original strain was isolated in 1980 in primary cynomolgus monkey kidney cells and has a serotype I and subgroup II antigenicity. The virus was serially passaged in African green monkey kidney cells; it was cultivated at 37 degrees C at the first stage of passages,
S, Matsuno +6 more
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Cold adaptation of microorganisms
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1990Psychrophilic and psychrotrophic microorganisms are important in global ecology as a large proportion of our planet is cold (below 5 °C); they are responsible for the spoilage of chilled food and they also have potential uses in low-temperature biotechnological processes.
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2001
In the last few years, increased attention has been focused on enzymes produced by cold-adapted micro-organisms. It has emerged that psychrophilic enzymes represent an extremely powerful tool in both protein folding investigations and for biotechnological purposes. Such enzymes are characterised by an increased thermosensitivity and, most of them, by a
D. Georlette +12 more
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In the last few years, increased attention has been focused on enzymes produced by cold-adapted micro-organisms. It has emerged that psychrophilic enzymes represent an extremely powerful tool in both protein folding investigations and for biotechnological purposes. Such enzymes are characterised by an increased thermosensitivity and, most of them, by a
D. Georlette +12 more
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Cold Adaptation and Thyroid Hormone Metabolism
Hormone and Metabolic Research, 2005Resting oxygen consumption and energy expenditure is sensitive to slight alterations in thyroid function. This means that timing and magnitude of cold adaptation would to some extent depend on thyroid function. Local thyroid hormone metabolism is important for energy expenditure and dissipation of heat in special tissues.
Laurberg, P. +2 more
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Advanced Healthcare Materials
AbstractCold‐adapted nanozymes represent a distinct class of nanomaterials that exhibit robust catalytic activity and stability under low‐temperature conditions (below 37 °C). By emulating the catalytic functions of natural enzymes, these nanozymes can overcome the inherent limitations of traditional enzymes, which typically suffer from the reduced ...
Tianye Zhang +7 more
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AbstractCold‐adapted nanozymes represent a distinct class of nanomaterials that exhibit robust catalytic activity and stability under low‐temperature conditions (below 37 °C). By emulating the catalytic functions of natural enzymes, these nanozymes can overcome the inherent limitations of traditional enzymes, which typically suffer from the reduced ...
Tianye Zhang +7 more
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