Results 281 to 290 of about 75,504 (352)

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

open access: yesAdvanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya   +10 more
wiley   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li   +11 more
wiley   +1 more source

Microstructure, Mechanical and Tribological Properties of Cold Sprayed Fe-Based Metallic Glass Coatings. [PDF]

open access: yesMaterials (Basel)
Góral A   +7 more
europepmc   +1 more source

An Investigation of the Influence of the Sequence of Laser Texturing and Heat Treatment Processes on the Coefficient of Friction of X165CrMoV12 Steel. [PDF]

open access: yesMaterials (Basel)
Sofronov Y   +9 more
europepmc   +1 more source

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