Results 91 to 100 of about 3,999,655 (320)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

AlphaBoot: accelerated container cold start using SmartNICs

open access: yesFrontiers in High Performance Computing
Scalability and flexibility of modern cloud application can be mainly attributed to virtual machines (VMs) and containers, where virtual machines are isolated operating systems that run on a hypervisor while containers are lightweight isolated processes ...
Shaunak Galvankar, Sean Choi
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Cold Start for the Green Innovation Machine [PDF]

open access: yes
This Policy Contribution accompanies the Policy Brief, Â?No Green Growth Without InnovationÂ?. Written by Senior Non-Resident Fellow Philippe Aghion, Senior Resident Fellow Reinhilde Veugelers and Researcher Clément Serre, this paper discusses the state ...
Clément Serre   +2 more
core   +1 more source

The Effect of Ambient Temperature on Cold Start Urban Traffic Emissions for a Real World SI Car [PDF]

open access: yes, 2004
The influence of ambient temperature on exhaust emissions for an instrumented Euro 1 SI car was determined. A real world test cycle was used, based on an urban drive cycle that was similar to the ECE urban drive cycle.
Andrews, G.E.   +6 more
core  

SAIN: Self-Attentive Integration Network for Recommendation

open access: yes, 2019
With the growing importance of personalized recommendation, numerous recommendation models have been proposed recently. Among them, Matrix Factorization (MF) based models are the most widely used in the recommendation field due to their high performance.
Kang, Jaewoo   +3 more
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Intelligent Service Recommendation for Cold-Start Problems in Edge Computing

open access: yesIEEE Access, 2019
Memory-based collaborative filtering (i.e., MCF) is regarded as an effective technique to recommend appropriate services to target users. However, if recommendation data are very sparse in the edge environment, traditional MCF-based recommendation ...
Yichao Zhou   +5 more
doaj   +1 more source

Representation Learning for cold-start recommendation

open access: yes, 2014
A standard approach to Collaborative Filtering (CF), i.e. prediction of user ratings on items, relies on Matrix Factorization techniques. Representations for both users and items are computed from the observed ratings and used for prediction ...
Artieres, Thierry   +2 more
core   +1 more source

The effect of ambient temperature on cold start urban traffic emissions for a real world SI car [PDF]

open access: yes, 2005
The influence of ambient temperature on exhaust emissions for an instrumented Euro 1 SI car was determined. A real world test cycle was used, based on an urban drive cycle that was similar to the ECE urban drive cycle.
Andrews, Gordon E   +6 more
core  

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