Results 141 to 150 of about 2,080,475 (297)

Predict multi-type drug-drug interactions in cold start scenario. [PDF]

BMC Bioinformatics, 2022
Liu Z, Wang XN, Yu H, Shi JY, Dong WM.
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

On free energy barriers in Gaussian priors and failure of cold start MCMC for high-dimensional unimodal distributions. [PDF]

Philos Trans A Math Phys Eng Sci, 2023
Bandeira AS, Maillard A, Nickl R, Wang S.   +3 more
europepmc   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

A Meta-adversarial Framework for Cross-Domain Cold-Start Recommendation

Data Science and Engineering
The cold-start problem in recommender systems has been facing a great challenge. Cross-domain recommendation can improve the performance of cold-start user recommendations in the target domain by using the rich information of users in the source domain ...
Yufang Liu, Shaoqing Wang, Xueting Li, Fuzhen Sun   +3 more
doaj   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Large Language Model Driven User Cold Start Recommendations [PDF]

The advent of new and powerful LLM models has given rise to innovative approaches to using large language models and recommendation systems. These models have been trained on a large corpus of data and world knowledge, which can be harnessed in ...
Dalvi, Shubham Prabhakar
core   +2 more sources

Deep transfer learning with multimodal embedding to tackle cold-start and sparsity issues in recommendation system. [PDF]

PLoS One, 2022
Jafri SIH, Ghazali R, Javid I, Mahmood Z, Hassan AAA.   +4 more
europepmc   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Mitigating cold-start problems in drug-target affinity prediction with interaction knowledge transferring. [PDF]

Brief Bioinform, 2022
Nguyen TM, Nguyen T, Tran T.
europepmc   +1 more source