Results 141 to 150 of about 7,593,003 (291)

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

Tourism Destination Recommender System for the Cold Start Problem

KSII Transactions on Internet and Information Systems, 2016
Xiaoyao Zheng, Yonglong Luo, Zhiyun Xu, Qingying Yu, Lin Lu   +4 more
openaire   +2 more sources

Editorial: Behind the Making [PDF]

, 2017
Few theses, proposals and books in game studies start without some statement of the importance of video games as a media format. However, despite this emphasis on the industry’s size and importance, very little academic attention goes toward what is ...
de Wildt, Lars, Azrioual, Samir, Murnane, Eric, Barr, Matthew, Assuncao, Carina, Dunne, Daniel Joseph, Berry, Landon Kyle, Butt, Mahli-Ann, Evans, Sarah Beth   +8 more
core  

Stretchable h‐BN/TPU Fibers for Passive‐Active Dual‐Mode Thermal Management and Wearable Haptic Interfaces

Advanced Science, EarlyView.
Optimized 30 wt.% h‐BN/TPU fibers create a thermal conductivity of 2.08 W·m−1·K−1 while retaining mechanical compliance (422% elongation at break). Woven fabrics reduce surface temperature by 5.7°C under simulated solar irradiation. Glove integration enables localized fingertip heating at 29.55°C·s−1 with a thermal relaxation time of approximately 20 s.
Yiwei Zhou, Shanshan Long, Bo Chen, Maohua Li, Linhong Li, Yue Qin, Rongjie Yang, Hanxi Chen, Cheng‐Te Lin, Yixiang Xu, Kean How Cheah, Nan Jiang, Jinhong Yu   +12 more
wiley   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

Applying Cross-Level Association Rule Mining to Cold-Start Recommendations

, 2008
We propose a novel hybrid recommendation algorithm for addressing the well-known cold-start problem in Collaborative Filtering (CF). Our algorithm makes use of Cross-Level Association RulEs (CLARE) to integrate content information about domain items into
Fu-lai Chung, Stephen Chi-fai Chan, Cane Wing-ki Leung   +2 more
core  

LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening

Advanced Science, EarlyView.
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico, Sara Rigolli, Julius Zimmermann, Melissa Pezzotti, Eloisa Torchia, Moises Di Sante, Ferdinando Auricchio, Francesco S. Pasqualini   +7 more
wiley   +1 more source

Do you have a Pop face? Here is a Pop song. Using profile pictures to mitigate the cold-start problem in Music Recommender Systems

, 2015
When a new user registers to a recommender system service, the system does not know her taste and cannot propose meaningful suggestions (cold-start problem).
Eugenio Tacchini
core  

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Cold Start Problem: a Lightweight Approach at ECML/PKDD 2011 - Discovery Challenge

, 2012
The paper presents our participation [5] at the ECML/PKDD 2011 - Discovery challenge for the task on the cold start problem. The challenge dataset was gathered from VideoLectures.Net web site that exploits a Recommender System (RS) to guide users ...
SEMERARO, Giovanni, Leo Iaquinta
core