Results 101 to 110 of about 2,553,529 (294)

Graph Neural Patching for Cold-Start Recommendations

The cold start problem in recommender systems remains a critical challenge. Current solutions often train hybrid models on auxiliary data for both cold and warm users/items, potentially degrading the experience for the latter. This drawback limits their viability in practical scenarios where the satisfaction of existing warm users/items is paramount ...
Hao Chen 0062, Yu Yang 0012, Yuanchen Bei, Zefan Wang, Yue Xu, Feiran Huang   +5 more
openaire   +3 more sources

LLM Reasoning for Cold-Start Item Recommendation

CoRR
Large Language Models (LLMs) have shown significant potential for improving recommendation systems through their inherent reasoning capabilities and extensive knowledge base. Yet, existing studies predominantly address warm-start scenarios with abundant user-item interaction data, leaving the more challenging cold-start scenarios, where sparse ...
Shijun Li 0002, Yu Wang 0158, Jin Wang, Ying Li 0124, Joydeep Ghosh, Anne Cocos   +5 more
openaire   +3 more sources

CDLD-CSP: Cold-Start Recommendation via Latent Adaptation With the CDLD Framework

IEEE Access
Cold-start recommendation remains a central challenge in systems with limited user-item interactions. To address this issue, a method termed CDLD-CSP (cold-start recommendation via latent adaptation with the CDLD framework) is proposed, combining cyclic ...
Younggi Hong, Sinwoo Park, Dohyoung Rim
doaj   +1 more source

IPTV program recommendation based on combination strategies

MATEC Web of Conferences, 2018
As a new interactive service technology, IPTV has been extensively studying in the field of TV pro-gram recommendation, but the sparse of the user-program rating matrix and the cold-start problem is a bottleneck that the program recommended accurately ...
Li Hao, Xia Huan, Kang Yan, Uddin Mohammad Nashir   +3 more
doaj   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

An Improved CF Algorithm Personalized Recommendation Model for E-Commerce Cold-Start Problems

Journal of Engineering, Project, and Production Management
Given the low recommendation accuracy of traditional algorithms in cold-start scenarios in e-commerce, this study proposes a new personalized recommendation algorithm.
Wenwei Chen
doaj   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

A Hybrid Recommendation System with Attribute Information for User Cold-Start Problem

, 2022
In recent years, with the rapid development of e-commerce, many online applications and media platforms have flourished. When users use these applications or media platforms, they are often faced with searching for items they are interested in from the ...
Yu, Teng-Chun
core  

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source