In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
Interpretable Drug-Target Prediction via Geometric Alignment: A Linear Alternative to Deep Architectural Complexity. [PDF]
Ghimire A +3 more
europepmc +1 more source
Photocatalytic Water Splitting on the Lunar Surface: Prospects for In Situ Resource Utilization
Water has been found in craters on the moon nearby locations which are illuminated >80% of the time. Photocatalysis uses energy from sunlight to drive chemical reactions such as water splitting to produce oxygen and hydrogen. It is a scalable technology that requires lighter equipment and utilizes resources available on the moon. ABSTRACT The discovery
Ranjani Kalyan +6 more
wiley +1 more source
Relation-Aware Heterogeneous Graph Learning for miRNA-Drug Response Association Prediction Under Cold-Start Generalization. [PDF]
Elbashir MK.
europepmc +1 more source
This review outlines critical engineering design rules for building artificial protective coatings on next‐generation lithium metal and silicon battery anodes. It highlights how balancing structural flexibility with strict electronic and ionic transport limits prevents early battery failure.
Surin Gupte, Vilas G. Pol
wiley +1 more source
Graph-Based Machine Learning for Predicting Drug-Drug Interactions: A Systematic Review. [PDF]
Reza MT +4 more
europepmc +1 more source
Smart‐Release Ion‐Exchanged Ca‐Montmorillonite for Corrosion Protection of AA2024 Aluminium Alloy
Smart‐release anticorrosion pigments based on Zn‐ and Mn‐modified montmorillonite were developed by ion exchange of Ca‐montmorillonite and evaluated for the protection of AA2024 aluminium alloy in artificial acid rain. Both modified pigments provided effective corrosion inhibition, with Zn‐modified montmorillonite (Zn‐MMT) achieving an inhibition ...
Sergiy Korniy +2 more
wiley +1 more source
Parabrachial neuropeptide Y Y1 receptor-expressing neurons govern the sensory dimension of neuropathic pain. [PDF]
Allen HN +12 more
europepmc +1 more source
The article overviews past and current efforts on caloric materials and systems, highlighting the contributions of Ames National Laboratory to the field. Solid‐state caloric heat pumping is an innovative method that can be implemented in a wide range of cooling and heating applications.
Agata Czernuszewicz +5 more
wiley +1 more source
Intraoperative Inner Experiences of Patients Undergoing Percutaneous Lung Tumor Radiofrequency Ablation Guided by CT in a Chinese Tertiary Hospital: A Qualitative Study. [PDF]
Lu X, Deng H, Wang H, Yu M.
europepmc +1 more source

