Results 101 to 110 of about 831,741 (298)

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun   +15 more
wiley   +1 more source

Cold acclimation and oxygen consumption in the thymus

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 2006
Mitochondrial uncoupling protein 1 is usually associated with brown adipose tissue but has recently been discovered in rat and mouse thymus. We wished to establish whether there was a thermogenic role for UCP 1 in thymus and thus examined the effect of 5 weeks cold-acclimation on rat thymus tissue abundance, thymocyte oxygen consumption, thymus ...
Brennan, Clare M.   +2 more
openaire   +4 more sources

Table6_Computational genomics insights into cold acclimation in wheat.XLSX

open access: yes, 2022
Development of cold acclimation in crops involves transcriptomic reprograming, metabolic shift, and physiological changes. Cold responses in transcriptome and lipid metabolism has been examined in separate studies for various crops.
Qiang Li (8118)   +4 more
core   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

DataSheet1_Computational genomics insights into cold acclimation in wheat.PDF

open access: yes, 2022
Development of cold acclimation in crops involves transcriptomic reprograming, metabolic shift, and physiological changes. Cold responses in transcriptome and lipid metabolism has been examined in separate studies for various crops.
Qiang Li (8118)   +4 more
core   +1 more source

Physiology of cold-acclimation in non-diapausing adults of Pyrrhocoris apterus (Heteroptera)

open access: yesEuropean Journal of Entomology, 2002
Chill tolerance (time of survival at -5°C) increased in non-diapausing (reproducing) adults of Pyrrhocoris apterus after a gradual, 4-week-long decrease in ambient temperature from 25° to 0°C.
Martin ŠLACHTA   +3 more
doaj   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

open access: yesAdvanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai   +18 more
wiley   +1 more source

Cold acclimation, deacclimation and memory in Arabidopsis [PDF]

open access: yes, 2018
Plants from temperate regions can be cold acclimated by exposure to low, but non-freezing temperatures resulting in improved freezing tolerance. Whereas the molecular and metabolic basis of cold acclimation has been investigated in detail, little is ...
Schaarschmidt, Stephanie   +10 more
core  

Table3_Computational genomics insights into cold acclimation in wheat.XLSX

open access: yes, 2022
Development of cold acclimation in crops involves transcriptomic reprograming, metabolic shift, and physiological changes. Cold responses in transcriptome and lipid metabolism has been examined in separate studies for various crops.
Qiang Li (8118)   +4 more
core   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li   +17 more
wiley   +1 more source

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