Results 151 to 160 of about 2,026,673 (304)

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Novel insights into retrogene evolution and cold adaptation in the alpine plant Crucihimalaya himalaica (Brassicaceae). [PDF]

BMC Biol
Hu Y, Qiao Q, Zhang R, Wang Q, Sun H, Zhang T.   +5 more
europepmc   +1 more source

Mining of key genes for cold adaptation from Pseudomonas fragi D12 and analysis of its cold-adaptation mechanism. [PDF]

Front Microbiol, 2023
Bao C, Li M, Zhao X, Shi J, Liu Y, Zhang N, Zhou Y, Ma J, Chen G, Zhang S, Chen H.   +10 more
europepmc   +1 more source

Programmable Functional Silicification of DNA Origami Nanostructures

Advanced Materials, EarlyView.
This work introduces additional functionality into silica‐coated DNA origami nanostructures using non‐standard silica precursors. A fluorescent precursor enables enhanced intracellular tracking, while a disulfide‐containing reagent yields redox‐responsive, degradable silica coatings.
Anna V. Baptist, Lasse Guericke, Philipp Mauker, Oliver Thorn‐Seshold, Amelie Heuer‐Jungemann   +4 more
wiley   +1 more source

A Hierarchical VvbHLH30-VvERF70-VvACS2 Module Orchestrates Ethylene Biosynthesis and Cold Adaptation in Grapevine. [PDF]

Plant Biotechnol J
Hou Y, Wong DCJ, Wang L, Kang Y, Zhou H, Kafle S, Liu Y, Xu M, Meng L, Liang Z, Yu G, Wang Q, Xin H.   +12 more
europepmc   +1 more source

The variability of PNPLA3 gene as a potential marker of cold adaptation in Yakuts. [PDF]

Int J Circumpolar Health, 2023
Pavlova NI, Bochurov AA, Alekseev VA, Sydykova LA, Dodokhov VV, Kurtanov KA, Krylov AV.   +6 more
europepmc   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Molecular mediators of cold adaptation in mammalian cells. [PDF]

Commun Biol
Dey P, Lal H, Saha P, Ramanathan A.
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Cold adaptation and horizontal gene transfer shape Antarctic sponge microbiomes. [PDF]

Microbiome
Manrique-de-la-Cuba MF, López-Rodríguez M, Abades S, Trefault N.   +3 more
europepmc   +1 more source