Results 111 to 120 of about 114,041 (266)

Applied winter biology: threats, conservation and management of biological resources during winter in cold climate regions. [PDF]

Conserv Physiol, 2023
Reeve C, Robichaud JA, Fernandes T, Bates AE, Bramburger AJ, Brownscombe JW, Davy CM, Henry HAL, McMeans BC, Moise ERD, Sharma S, Smith PA, Studd EK, O'Sullivan A, Sutton AO, Templer PH, Cooke SJ.   +16 more
europepmc   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Signatures of selection in indigenous Chinese cattle genomes reveal adaptive genes and genetic variations to cold climate. [PDF]

J Anim Sci, 2023
Huang N, Zhao L, Wang J, Jiang Q, Ju Z, Wang X, Yang C, Gao Y, Wei X, Zhang Y, Xiao Y, Liu W, Lu S, Huang J.   +13 more
europepmc   +1 more source

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

Advanced Science, EarlyView.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang, Peipei Song, Xueji Wu, Lei Wang, Wei Xie, Pinning Feng, Chao Cheng, Jianping Guo   +7 more
wiley   +1 more source

Gut microbiota differs between two cold-climate lizards distributed in thermally different regions. [PDF]

BMC Ecol Evol, 2022
Chen JQ, Zhang LW, Zhao RM, Wu HX, Lin LH, Li P, Li H, Qu YF, Ji X.   +8 more
europepmc   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Assessment of stormwater discharge contamination and toxicity for a cold-climate urban landscape. [PDF]

Environ Sci Eur, 2022
Popick H, Brinkmann M, McPhedran K.
europepmc   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Cold Climate Impact on Air-Pollution-Related Health Outcomes: A Scoping Review. [PDF]

Int J Environ Res Public Health, 2022
Wine O, Osornio Vargas A, Campbell SM, Hosseini V, Koch CR, Shahbakhti M.   +5 more
europepmc   +1 more source

The Ainu and the Cold Climate

The Quaternary Research (Daiyonki-Kenkyu), 1974
The study of the language or foklore of the tribe may suggest what kind of the climate their ancestors experienced in the past. The author has tried to discover this from a study of the Ainu language and its oral tradition.The Ainu language, like English or Japanese, does not have many different morphemes for snow or ice when compared with Eskimo or ...
openaire   +2 more sources