Results 281 to 290 of about 661,161 (337)

Aquatic Thermal and Photochemical Reactivity of <i>N</i>-(1,3-Dimethylbutyl)-<i>N</i>'-phenyl-<i>p</i>-phenylenediamine (6PPD), <i>N</i>-Isopropyl-<i>N</i>'-phenyl-<i>p</i>-phenylenediamine (IPPD), and 6PPD-quinone. [PDF]

Environ Sci Technol
Platt KL, Yushchenko O, Laszakovits JR, Zhang Y, Pflug NC, McNeill K.   +5 more
europepmc   +1 more source

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

Gravitational Hamiltonian Systems and the Retarded Gravity Inequality. [PDF]

Entropy (Basel)
Yahalom A.
europepmc   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Manifesto: challenging the standard cosmological model. [PDF]

Philos Trans A Math Phys Eng Sci
Binney J, Mohayaee R, Peacock J, Sarkar S.   +3 more
europepmc   +1 more source

NIR Driven Pd/Cerium Oxide Nano‐Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy

Advanced Science, EarlyView.
In vivo SALI therapy is achieved by scavenging intracellular ROS levels, downregulating inflammatory factors expression levels, inducing macrophage M2 directional polarization, and activating Keap1/Nrf‐2/HO‐1 pathway to reprogram redox homeostasis, induce cellular autophagy, reduce systemic inflammation, and promote liver tissue repair. Abstract Sepsis
Tao Qin, Lian Qin, Yang Zhao, Yin Chen, Qianyue Liu, Xiaoguang Lin, Yongfeng Lan, Yaohui Huang, Yan Liu, Ke Zhang, Lifan Pan, Jiaxiao Li, Kunpeng Duan, Hao Liang, Mingjing Yin, Guiyang Fan, Lian Liu, Yu Deng, Lin Liao, Danke Su, Ming Gao, Junyu Lu   +21 more
wiley   +1 more source

Missing interstellar sulfur in inventories of polysulfanes and molecular octasulfur crowns. [PDF]

Nat Commun
Herath A, McAnally M, Turner AM, Wang J, Marks JH, Fortenberry RC, Garcia-Alvarez JC, Gozem S, Kaiser RI.   +8 more
europepmc   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Storage Behavior and Response to Low-Cost Postharvest Technologies of the Underutilized Purple Yampee (<i>Dioscorea trifida</i> L.f.). [PDF]

Foods
Medina-López SV, Jola Hernández JA, Hernández-Gómez MS, Fernández-Trujillo JP.   +3 more
europepmc   +1 more source