Results 311 to 320 of about 801,925 (377)

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Photosynthetic Electron Transport in Winter Wheat: Responses to Low-Temperature and Weak-Light Condition. [PDF]

Cells
Yang C, Liu M, Du S, Zhang D, Li X, Wu L, Shi Y, Fang B, Yan G, Wei F.   +9 more
europepmc   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Search of high-frequency variations of fundamental constants using spin-based quantum sensors. [PDF]

Natl Sci Rev
Kong X, Zhang Y, Ji C, Chang S, Chen Y, Bian X, Duan CK, Huang P, Du J.   +8 more
europepmc   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Novel Anthraquinone Chlorination Contributes to Pigmentation and ATP Formation in Thermomyces dupontii. [PDF]

Microb Biotechnol
Wang D, Dai G, He J, Si H, Liao C, Wang W, Zuo Z, Li S, Niu X.   +8 more
europepmc   +1 more source

Ultrathin Multi‐Doped Molybdenum Oxide Nanodots as a Tunable Selective Biocatalyst

Advanced Science, EarlyView.
This paper presents an advanced multi‐doped molybdenum oxide nanodots with tunable ammonium and proton doping, exhibiting strong ROS generation. The material demonstrates ultrafast and complete dye degradation and unique selective toxicity toward cancer cells, highlighting its promising potential for cancer therapy applications.
Bao Yue Zhang, Farjana Haque, Shwathy Ramesan, Sanjida Afrin, Muhammad Waqas Khan, Haibo Ding, Xin Zhou, Qijie Ma, Jiaru Zhang, Rui Ou, Md Mohiuddin, Enamul Haque, Yichao Wang, Azmira Jannat, Yumin Li, Robi S. Datta, Kate Fox, Guolang Li, Hujun Jia, Jian Zhen Ou   +19 more
wiley   +1 more source

Microbial responses under sunlight-dark conditions accelerate sequestration and transformation of soil biogenic, redox and non-redox components, including As and Hg. [PDF]

Sci Rep
Mohinuzzaman M, Zhang J, Mostofa MGK, Sun R, Zheng W, Chen J, Senesi N, Senesi GS, Vione D, Li SL, Yuan J, Liu CQ.   +11 more
europepmc   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

Advanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li, Xinrui Li, Yuhui Du, Sijie Chen, Xiaoniu He, Zhangrong Xie, Zhiqing Zhou, Huijie Zhao, Xiaofei Zeng, Guoan Chen   +9 more
wiley   +1 more source

Cold Plasma-Induced Changes in Polyethylene Particles and Their Binding Affinity to Selected Pharmaceuticals. [PDF]

Molecules
Wypart-Pawul A, Karwowska B, Caban R, Grobelak A.   +3 more
europepmc   +1 more source