Results 91 to 100 of about 966,468 (273)

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

Bee pollen as functional food and environmental bioindicator: current evidence and future challenges

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Bee pollen (BP), a plant‐derived product collected by honey bees, is increasingly promoted as a functional food due to its content of proteins, essential amino acids, lipids, vitamins, minerals, and bioactive compounds such as polyphenols and flavonoids.
Luigi Parrotta, Stefano Del Duca
wiley   +1 more source

MCP results in a decreased mechanicaland cold hypersensitivity.

, 2016
Mechanical (B) and cold (C) pain-related hypersensitivity developed after treatment with MCP (100 mg/kg/day) and Rapa (1 mg/kg/day) at the indicated time after surgery. n = 8. Data are expressed as mean ± SD. *p< 0.05 vs control, # p< 0.05 vs MCP group.
Zisheng Ai (602117), Qi Han (499168), Zhicong Ma (1660621), Xiaolei Wang (139592), Yongjun Zheng (1660624)   +4 more
core  

Management of dentine hypersensitivity [PDF]

, 2010
Dentine hypersensitivity may be defined as short, sharp pain arising from exposed dentine typically in response to chemical, thermal or osmotic stimuli that cannot be explained as arising from any other forms of dental defect or pathology.1 Dentine ...
Chu, CH
core  

Modulation of oxidative metabolism and quality preservation of strawberries by a CMC–alginate bilayer edible coating during cold storage

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Strawberries are highly perishable fruits characterized by rapid postharvest deterioration, leading to significant quality losses and reduced marketability. In this study, a bilayer edible coating based on carboxymethylcellulose and sodium alginate was evaluated for its ability to preserve strawberry quality during cold storage ...
Ilenia Pellicano, Riccardo Riggi, Elvira Ferrara, Danilo Cice, Margherita Modesti, Milena Petriccione, Andrea Bellincontro   +6 more
wiley   +1 more source

Cannabinoid 1 receptor knockout mice display cold allodynia, but enhanced recovery from spared-nerve injury-induced mechanical hypersensitivity

Molecular Pain, 2016
Background The function of the Cannabinoid 1 receptor (CB1R) in the development of neuropathic pain is not clear. Mounting evidence suggest that CB1R expression and activation may contribute to pain.
Alexandra Sideris PhD, Boris Piskoun BS, Lori Russo MD, Monica Norcini PhD, Thomas Blanck MD PhD, Esperanza Recio-Pinto PhD   +5 more
doaj   +1 more source

Structurally competent care for families facing the continuous traumatic stress of community violence and systemic racism

Journal of Traumatic Stress, EarlyView.
Abstract In racially and economically segregated communities, structural violence and chronic adversity perpetuate the risk for community violence and related trauma exposure. Despite widespread awareness of community violence, urban youth of color are among those least likely to have access to services that promote trauma recovery. When these youth do
Bradley C. Stolbach, Seeba Anam, Keyona Allen, Emma‐Lorraine Baaba Bart‐Plange, Royce Lee, Aashana Daru, Angel Boulware, Sonya Mathies Dinizulu   +7 more
wiley   +1 more source

Envolvimento do receptor de potencial transitório A1 (TRPA1) na manutenção da hiperalgesia mecânica e térmica (Frio) na inflamação persistente [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pos-Graduação em Farmacologia, Florianópolis, 2010O presente estudo investiga o papel do receptor TRPA1 no esenvolvimento e manutenção da ...
Costa, Diogo Santos Martins da
core  

Effect of ifenprodil on oxaliplatin-induced mechanical and cold hypersensitivity at day 3 in rats fed with a normal diet.

, 2013
Neuropathic pain was induced in rats fed with normal diet by a single i.p. injection of oxaliplatin (OXA) at 6 mg/kg on day 0. (A) Mechanical hypersensitivity was assessed before and 3 days after oxaliplatin injection, and then at 1, 2, 8 and 24 h after ...
Jacques-Philippe Moulinoux (478167), Mathilde Bayet-Robert (385297), Alain Eschalier (209750), Bruno Pereira (415597), Laurence Daulhac (441656), Jérémy Ferrier (478166), David Balayssac (478168), Denis Pezet (282342)   +7 more
core   +1 more source

The Nav1.9 Channel Is a Key Determinant of Cold Pain Sensation and Cold Allodynia [PDF]

, 2015
International audienceCold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood.
Patrick Delmas, Bonnet, Caroline, Stéphane Lolignier, Jérôme Ruel, Noël, Jacques, Delmas, Patrick, Caroline Bonnet, Ferrier, Jérémy, Busserolles, Jérôme, Padilla, Françoise, Chapuy, Eric, Jérémy Ferrier, Prival, Laetitia, Christelle Gaudioso, Rodat-Despoix, Lise, Valentine Bouvier, Youssef Aissouni, Jacques Noël, Ruel, Jérôme, Lise Rodat-Despoix, Eschalier, Alain, Laetitia Prival, Alain Eschalier, Stéphane Lolignier, Eric Chapuy, Françoise Padilla, Lolignier, Stéphane, Aissouni, Youssef, Gaudioso, Christelle, Muriel Amsalem, Bouvier, Valentine, Amsalem, Muriel, Jérôme Busserolles   +32 more
core   +1 more source