Peripheral kappa opioid receptors modulate cold hypersensitivity in a mouse model of chemotherapy-induced neuropathy. [PDF]
Madasu MK +10 more
europepmc +1 more source
Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra +4 more
wiley +1 more source
Network Pharmacology-Based Exploration of Complementary Molecular Mechanisms of Heat-Clearing (Scutellariae Radix, Coptidis Rhizoma) and Blood-Tonifying Herbs (Angelicae Sinensis Radix, Paeoniae Radix Alba) in Cold Hypersensitivity in Hands and Feet. [PDF]
Lee E +6 more
europepmc +1 more source
Spinal cord stimulation prevents paclitaxel-induced mechanical and cold hypersensitivity and modulates spinal gene expression in rats. [PDF]
Sivanesan E +10 more
europepmc +1 more source
ABSTRACT Objective This scoping review aimed to (1) map, analyse, interpret and synthesize data from clinical trials on topical alternatives used to prevent and/or reduce sensitivity caused by in‐office tooth bleaching; and (2) characterize the available evidence on their use for managing sensitivity.
Erik Vinícius Martins Jácome +3 more
wiley +1 more source
The Relationship between Cold Hypersensitivity in the Hands and Feet and Health-Related Quality of Life in Koreans: A Nationwide Population Survey. [PDF]
Bae KH, Lee Y, Go HY, Kim SJ, Lee SW.
europepmc +1 more source
Machine Learning Model for Predicting Postoperative Pain in Cases of Irreversible Pulpitis
ABSTRACT Aim Postoperative pain is a frequent clinical concern following endodontic treatment. This study aimed to develop and validate supervised machine learning models to predict the occurrence of postoperative pain in cases of irreversible pulpitis.
Pedro Felipe de Jesus Freitas +9 more
wiley +1 more source
The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson +3 more
wiley +1 more source
A new biomarker for screening Hiesho (cold hypersensitivity) in young females through measurement of the foot temperature-recovery rate after a cooling test. [PDF]
Wang T, Shima K, Ohno Y, Endo M.
europepmc +1 more source
BMAL1 in Anterior Cingulate Cortex Pyramidal Neurons Relieves Pulpitis‐Induced Nocturnal Pain
ABSTRACT Aim Nocturnal exacerbation of pulpitis‐induced pain severely disrupts patients' sleep and quality of life, increasing emergency dental care burden. However, the exact mechanisms underlying nocturnal pain remain poorly understood, limiting the development of targeted analgesic strategies.
Yuting Bai +8 more
wiley +1 more source

