This study demonstrates that activation of Piezo1 channels in goblet cells by intestinal mechanical stimulation modulates ER calcium homeostasis via calcium ion (Ca2+) flux, which in turn regulates Mucin2 production and synthesis through the IRE1α‐XBP1. Intraperitoneal administration of Yoda1 alleviates mucus barrier impairment in DSS/WAS‐treated mice.
Jiandi Wu +13 more
wiley +1 more source
K2P channels as emerging therapeutic targets for pain: insights from functional studies and transcriptomic analyses. [PDF]
Gilbert N +6 more
europepmc +1 more source
ABSTRACT Beetroot juice (BJ) and caffeine (CAF) are well‐established ergogenic aids for exercise performance. However, little is known about their efficacy and interaction within the specific context of a judo competition day. This study investigated the acute effects of BJ, CAF, and their combination (BJCAF) on judo‐specific performance across a ...
Sefer Karabağ +6 more
wiley +1 more source
Traditional Chinese Medicine for Cough Variant Asthma: Bridging TCM Syndrome Differentiation with Modern Immunological Mechanisms and Clinical Translation - A Narrative Review. [PDF]
Luo D, Yang Y, Tian J, Li J.
europepmc +1 more source
Integration of Aromatherapy and Essential Oils in Asthma Symptom Relief: A Narrative Review
ABSTRACT Background and Aims Asthma affects 262 million people globally, causing 455,000 preventable deaths, with higher mortality in low‐resource areas due to limited diagnosis and treatment. Aromatherapy, using bioactive essential oils (EOs), has emerged as a promising complementary approach for asthma symptom management.
Alex Odoom
wiley +1 more source
Clinical comparison of CAD/CAM nanohybrid composite and hybrid ceramic overlays in children with molar-incisor hypomineralisation: a split-mouth prospective randomized clinical trial. [PDF]
Akça A, Eren F, Kargül B.
europepmc +1 more source
A TRIP‐nano killer silencing the pain pacemakers
The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley +1 more source
Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral ...
Kar Yee Phoon, Rob Ward
wiley +1 more source
Associations of Dietary Patterns and Allergies With Asthma Among University Students in Bangladesh: A Cross-Sectional Study. [PDF]
Akter M, Muktarul M, Faruque A.
europepmc +1 more source

