Results 231 to 240 of about 27,811 (300)

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Experiences of social support and the role of engagement in a digital educational support group for adolescent mothers' health in the Dominican Republic. [PDF]

PLOS Digit Health
Lopez AR, Haight E, Guijosa L, Williams B, Unger J, Messina L, Halpern M, Stonbraker S, Ronen K.   +8 more
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Bacterial community structure associated with smokeless tobacco reference products under different storage conditions and durations. [PDF]

Front Public Health
Liu S, Greenhut IV, Moe LA.
europepmc   +1 more source

Cold source moderator vessel development for the High Flux Isotope Reactor: Thermal-hydraulic studies

, 1998
Paul T. Williams, A.T. Lucas, M.W. Wendel   +2 more
openalex   +1 more source

SELECT: Social and Collaborative Filtering of Web Documents and News [PDF]

, 1999
Alton-Schiedl, R., Ekhall, J., Kovacs, L., Lueg, C., Mason, D., Messnarz, R., Micsik, A., Nichols, David, Palme, J., Procter, R., Stupazzini, E., Tholerus, T., van Geloven, O., Vassali, M., Wheeler, M.   +14 more
core  

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Exposing omitted moderators: Explaining why effect sizes differ in the social sciences. [PDF]

Proc Natl Acad Sci U S A
Krefeld-Schwalb A, Sugerman ER, Johnson EJ.   +2 more
europepmc   +1 more source

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

Advanced Science, EarlyView.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin, Shulan Xiao, Krishna Jayant   +2 more
wiley   +1 more source

A Manufacturing Technique for Binary Clathrate Hydrates for Cold and Very Cold Neutron Production. [PDF]

Materials (Basel)
Czamler V, Desmedt A, Hansen TC, Wagner R, Zimmer O.   +4 more
europepmc   +1 more source