Results 111 to 120 of about 1,531,075 (291)
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Pilot Production of High Pressure Boiler Tube of T91 Steel at Tianjin Pipe Group Corp Ltd
Teshugang, 2007 The cold rolled tube φ51 mm×6 mm and φ60 mm×6 mm of T91(10Cr9MolVNb)steel piot produced by gcrap + DRI+ pig iron- 100t UHP EAF-LF(VD)-CCM(EMS) φ210 mm round billet-hot rolling tube φ89 mm×7 mm -cold rolling process at Tianjin Pipe. The continuous
谷立功, 肖功业, 王国亮
doaj
Effect of Cold Temperature and Food Restriction on Energy Metabolism and Thermogenesis in Eothenomys miletus [PDF]
Journal of Stress Physiology & Biochemistry, 2014 The aim of the present study was to examine the energy strategy in response to the cold temperature and food shortage. The survival rate, body mass, body fat content, serum leptin levels, basal metabolic rate (BMR) and nonshivering thermogenesis (NST) as
Wan-Long Zhu +4 more
doaj
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
, 2021 D8.3 POPD - Requirement No. 7 is one of the three ethics deliverables of the SESAR 2020 Exploratory Research action BEACON. This deliverable describes that the data the consortium intends to process is relevant and limited to the purposes of the research
Kelly, H. +3 more
core
AS-905-20 Resolution Opposing the Implementation of AB1460/Education Code 89032 (The California State University Ethnic Studies Undergraduate Graduation Requirement) in General Education (Title V) [PDF]
, 2020 Opposing implementation of AB1460, faculty should control the curriculum, request the rescinding of modification to Title V, and reaffirms the Ethnic Studies requirement should be fulfilled as a campus-based university graduation ...
Cal Poly Ethnic Studies Requirement Working Group,
core
Development of Chromium-Free Passivating and Finger-Mark Proofing Hot-Dip Zinc-Coated Steel Sheet
Teshugang, 2014 According to the quality issues including finger-mark proofing firm thickness un-uniform, roll marks sensitiveness to form marks etc. in production of chromium-free passivating and finger-mark proofing cold-rolled 0. 3 〜2.
孔凡庆 +5 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source