Results 51 to 60 of about 1,531,075 (291)

Memory of the Vernalized State in Plants including the Model Grass Brachypodium distachyon

open access: yesFrontiers in Plant Science, 2014
Plant species that have a vernalization requirement exhibit variation in the ability to remember winter—i.e., variation in the stability of the vernalized state.
Daniel P Woods   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Water supply in cold regions

open access: yes, 2020
WATER SUPPLY IN COLD REGIONS Amos J. Al ter January 1969 GB 2401 ,U58m lll-C5a 1969 LD U.S. ARMY MA T ERIE L COMMAND TERRE S TRIA L SCIENCES CENTER REGIONS RESEARCH A ENGINEERING LABORATORY HANOVER, NEW HAMPSHIRE T H I S D O C U M E N T H A S B E E N A P
Cold Regions Research and Engineering Laboratory (U.S.)
core  

Germination of dimorphic seeds of Suaeda aralocaspica in response to light and salinity conditions during and after cold stratification [PDF]

open access: yesPeerJ, 2017
Cold stratification is a requirement for seed dormancy breaking in many species, and thus it is one of the important factors for the regulation of timing of germination. However, few studies have examined the influence of various environmental conditions
Hong-Ling Wang, Chang-Yan Tian, Lei Wang
doaj   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

WASTAGE OF UNDERGROUND WATER - STEPS TOWARDS A TRAP? [PDF]

open access: yesExploratory Animal and Medical Research, 2015
Underground water is used indiscriminately for the purposes like agriculture, serving purposes of urban people, cold drink and mineral water manufacturing etc.
Shibabrata Pattanayak
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Determination of Chilling and Heat Requirement of Four Apricot Cultivars of Khorasan Razavi Province

open access: yesMajallah-i ̒Ulum-i Bāghbānī, 2017
Introduction:Dormancy is one of the most important stages in the life cycle of temperate plants and plants are required to exit from it with supply of chill unit. Flowering is defined with chilling and heat requirement. Owing to low chilling requirement,
zohreh hoshyar   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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