Results 151 to 160 of about 244,474 (303)
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin +12 more
wiley +1 more source
NiCoCrAlX (X = Y, Hf and Si) Bond Coats by Cold Spray for High Temperature Applications. [PDF]
Cojocaru CV, Aghasibeig M, Irissou E.
europepmc +1 more source
Review and test of chilldown methods for space-based cryogenic tanks [PDF]
The literature for tank chilldown methods applicable to cryogenic tankage in the zero gravity environment of earth orbit is reviewed. One method is selected for demonstration in a ground based test.
Chato, David J., Sanabria, Rafael
core +1 more source
A smart power‐generating coating is developed to harvest energy from both ambient humidity and impacting liquid droplets. The integrated system delivers sustained open‐circuit voltages of 0.85 V from moisture and up to 36 V from droplets. Its scalable coating architecture enables a continuous power supply for low‐power electronic devices.
Liang Ma +5 more
wiley +1 more source
Effect of Various Heat Treatments on the Microstructure of 316L Austenitic Stainless Steel Coatings Obtained by Cold Spray. [PDF]
Brassart LH +7 more
europepmc +1 more source
Cleaning of a thermal vacuum chamber with shrouds in place [PDF]
In February, 1991, a failure of a rotary booster pump caused the diffusion pumps to backstream into a 10 ft x 15 ft thermal vacuum chamber. Concerns existed about the difficulty of removing and reinstalling the shrouds without causing leaks.
Bond, William R.
core +1 more source
Non‐Equilibrium Synthesis Methods to Create Metastable and High‐Entropy Nanomaterials
ABSTRACT Stabilizing multiple elements within a single phase enables the creation of advanced materials with exceptional properties arising from their complex composition. However, under equilibrium conditions, the Hume–Rothery rules impose strict limitations on solid‐state miscibility, restricting combinations of elements with mismatched crystal ...
Shuo Liu +3 more
wiley +1 more source
Evaluation of the Fatigue Behaviour and Failure Mechanisms of 52100 Steel Coated with WIP-C1 (Ni/CrC) by Cold Spray. [PDF]
Goanta V +7 more
europepmc +1 more source
A yolk@shell structured photothermal evaporator was prepared via simple sol‐gel and spray coating methods. By taking advantage of the unique yolk@shell structure, the position of the TE module within the evaporator can be optimized without affects its water evaporation performance. This results in efficient and stable evaporation (3.08‐3.17 kg m−2 h−1)‐
Minrui Zhan +13 more
wiley +1 more source

