Results 151 to 160 of about 93,328 (309)

Metallic seal for thermal barrier coating systems [PDF]

The invention is particularly concerned with sealing thermal barrier coating systems of the type in use and being contemplated for use in diesel and other internal combustion engines.
Miller, Robert A.
core   +1 more source

High‐Efficiency CO2 Electrolysis Enabled by Interface‐Engineered Composite Electrolytes in Ni‐Based SOEC

Advanced Science, EarlyView.
This study addresses the critical issue of delamination between YSZ and GDC electrolytes in SOECs, which is caused by Thermal deformation disparity. A novel YSZ‐GDC composite interlayer, fabricated using a simple dip‐coating method, is introduced to solve this problem. This layer effectively suppresses delamination by mitigating thermal stress.
Rustam Yuldashev, Hyunchul Jung, Ji Hoon Park, Jin Hee Lee, Min‐Chul Kim   +4 more
wiley   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Smart Energy–Harvesting Coating for Moisture–Droplets Based on Ionic Diodes and Transistor–Like Structures

Advanced Science, EarlyView.
A smart power‐generating coating is developed to harvest energy from both ambient humidity and impacting liquid droplets. The integrated system delivers sustained open‐circuit voltages of 0.85 V from moisture and up to 36 V from droplets. Its scalable coating architecture enables a continuous power supply for low‐power electronic devices.
Liang Ma, Mengdi Liu, Yuxi Yang, Zehao Wang, Lan Shi, Limin Wu   +5 more
wiley   +1 more source

Non‐Equilibrium Synthesis Methods to Create Metastable and High‐Entropy Nanomaterials

Advanced Science, EarlyView.
ABSTRACT Stabilizing multiple elements within a single phase enables the creation of advanced materials with exceptional properties arising from their complex composition. However, under equilibrium conditions, the Hume–Rothery rules impose strict limitations on solid‐state miscibility, restricting combinations of elements with mismatched crystal ...
Shuo Liu, Chaochao Dun, Jeffrey J. Urban, Mark T. Swihart   +3 more
wiley   +1 more source

A Yolk@Shell Photothermal Structure for Integrated Solar‐Driven Undrinkable Water Purification and Thermoelectric Power Generation

Advanced Science, EarlyView.
A yolk@shell structured photothermal evaporator was prepared via simple sol‐gel and spray coating methods. By taking advantage of the unique yolk@shell structure, the position of the TE module within the evaporator can be optimized without affects its water evaporation performance. This results in efficient and stable evaporation (3.08‐3.17 kg m−2 h−1)‐
Minrui Zhan, Xiang Fu, Yumei He, Manman Zhao, Xi Zhang, Rong Liu, Haonan Yang, Ming Yang, Huiyu Yang, Pei Lyu, Jiehao Du, Shaojin Gu, Xin Liu, Bin Shang   +13 more
wiley   +1 more source

Meter‐Scale Ultra‐Large‐Area Flexible Electroluminescent Devices Enabled by Aerosol Spraying

Advanced Science, EarlyView.
This work presents a simple aerosol spraying method using modified luminescent ink to fabricate meter‐scale flexible alternating current electroluminescent (ACEL) devices. Enhanced particle dispersibility and film uniformity yield impressive brightness up to 500 cd m−2, positioning these devices as effective luminous navigation signs for industrial ...
Hao Song, Liang Yi, Lixiang Huang, Wajid Ali, Linhan Cai, Chao Wang, Jianhua Huang, Ziwei Li, Anlian Pan   +8 more
wiley   +1 more source

Neuromorphic Motor Control with Electrolyte‐Gated Organic Synaptic Transistors

Advanced Electronic Materials, EarlyView.
Electrolyte‐gated organic synaptic transistor (EGOST)‐based neuromorphic motor control systems integrate sensing, processing, and actuation by mimicking biological synapses. With advantages such as low power consumption, tunable synaptic plasticity, and mechanical flexibility, they are emerging as next‐generation core technologies for real‐time ...
Sung‐Hwan Kim, Ju‐Hyeok Yun, Hea‐Lim Park, Sin‐Hyung Lee   +3 more
wiley   +1 more source