Results 211 to 220 of about 40,088 (283)

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Co-ordinated shifts in deep-water formation and Gulf Stream migration during abrupt climate changes. [PDF]

Nat Commun
Zhu F, Carter-Champion A, Wharton JH, Bracamontes-Ramírez J, Burke A, de Menocal PB, Fairman D, Keigwin LD, Marchitto TM, Papachristopoulou E, Rae JWB, Rosenthal Y, Zhao N, Thornalley DJR.   +13 more
europepmc   +1 more source

Dual‐targeted nanomedicine delivering doxorubicin and nitric oxide for tumor immunomodulation and synergistic therapy

BMEMat, EarlyView.
The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng, Wei Chen, Shuyu Li, Xiaomin Ma, Yanfeng Dai, Yan Wang, Changqiang Xie, Yazhe Xiao, Hesong Han, Yumiao Zhang, Junjie Wang   +10 more
wiley   +1 more source

Breaching the immune-cold barrier in pMMR/MSS metastatic colorectal cancer: emerging strategies beyond standard care. [PDF]

Front Immunol
Kang W, Zhang Z, Li W, Zhang Q, Li N, Jiang Y, Zhang J, He Y.   +7 more
europepmc   +1 more source

Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris

Biological Diversity, EarlyView.
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu, Jia Li, Xin Liu, Xue‐Jun Ge, Hui‐Run Huang   +4 more
wiley   +1 more source

Clinically oriented immune heterogeneity in prostate cancer: emerging targets and strategies. [PDF]

Front Immunol
Zhan M, Zhao B, Wu J, Li K, Chen Y, Chen H, Zhao L, Zhu J.   +7 more
europepmc   +1 more source

A mosaic of microclimates: biodiversity outcomes and wildlife habitat potential in large‐scale solar facilities

Biological Reviews, EarlyView.
ABSTRACT The rapid global expansion of photovoltaic (PV) solar facilities, now comprising nearly 80% of the recent and projected growth of renewable electricity, represents one of the most significant land‐use changes of the 21st century. While PV facilities are critical for decarbonising energy systems, their large spatial footprint and infrastructure
Tom Armstrong, Caleb L. Loughran, Joshua R. Ennen, Kristoffer H. Wild, Eric J. Nordberg   +4 more
wiley   +1 more source

Machine learning-based risk stratification of early graft failure in simultaneous pancreas-kidney transplantation. [PDF]

Sci Rep
Altamimi O, Nabulsi H, Al-Shehab M, Abbasi Y.   +3 more
europepmc   +1 more source

Critical Success Factors for Enhancing the Circular Economy Performance of Last‐Mile Cold Chain Logistics Packaging for Urban Agricultural Products

Business Strategy and the Environment, EarlyView.
ABSTRACT With the increasing demand for high‐quality agricultural products, the agricultural cold‐chain logistics packaging (ACLP) industry faces significant environmental pressure and circular economy issues. This study analyzes the critical success factors (CSFs) that would enhance ACLP circular economy performance (CEP). The adversarial interpretive
Miao Su, Chunyu Liu, Shucheng Duan, Taewoo Roh   +3 more
wiley   +1 more source

A conceptual blueprint for "turning cold to hot" in Osteosarcoma: from TME stratification hypotheses to adaptive therapeutic prospects. [PDF]

Cell Commun Signal
Yang B, Liu S, Liu B, Ye T, Ma X, Song T.   +5 more
europepmc   +1 more source