Results 141 to 150 of about 8,842,438 (372)

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source

A protein model exhibiting three folding transitions

, 2000
We explain the physical basis of a model for small globular proteins with water interactions. The water is supposed to access the protein interior in an "all-or-none" manner during the unfolding of the protein chain.
Alex Hansen, Anfinsen, Audun Bakk, Bae, Bakk, Baldwin, Baldwin, Bryngelson, Bryngelson, Chen, Cohn, Frank, Galzitskaya, Griko, Hansen, Hansen, Hansen, Jackson, Kim Sneppen, Makhatadze, Makhatadze, Micheletti, Muñoz, Privalov, Privalov, Privalov, Privalov, Privalov, Privalov, Shortle, Wang, Zwanzig   +31 more
core   +1 more source

Microcystin aids in cold temperature acclimation: Differences between a toxic Microcystis wildtype and non-toxic mutant. [PDF]

Harmful Algae, 2023
Stark GF, Martin RM, Smith LE, Wei B, Hellweger FL, Bullerjahn GS, McKay RML, Boyer GL, Wilhelm SW.   +8 more
europepmc   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Temperature Changes of Pulmonary Blood During Exposure to Cold [PDF]

, 1953
G. W. Mather, G Nahas, Allan Hemingway
openalex   +1 more source

TRPA1 Channels Mediate Cold Temperature Sensing in Mammalian Vagal Sensory Neurons: Pharmacological and Genetic Evidence

Journal of Neuroscience, 2008
Cold thermoreceptors have been described in different territories of the vagus nerve. Application of cold temperature to these visceral afferents can evoke major protective reflexes and thermoregulatory responses.
O. Fajardo, V. Meseguer, C. Belmonte, F. Viana   +3 more
semanticscholar   +1 more source

A mechanistic view of the use of cold temperature in the treatment of cancer. [PDF]

iScience, 2023
Grazioso TP, Djouder N.
europepmc   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Do Different Next-to-Skin Garments Change Thermal Sensation, Jump Height and Landing Knee Valgus After Cold Exposure?

Applied Sciences
Exposure to the cold can negatively affect muscle performance. This study compared the effects of two different full-length, lower body, next-to-skin garments on thermal sensation, countermovement jump (CMJ) height and knee frontal plane angle upon ...
Ben Kasehagen, Susan Morris, Kevin Netto
doaj   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
wiley   +1 more source