Results 121 to 130 of about 1,534,889 (302)

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

Screening for cold tolerance resources in maize seedlings and analysis of leaf cell responses

Frontiers in Plant Science
Using 63 maize varieties as materials, this study employed indoor low-temperature stress testing methods to evaluate cold tolerance during the seedling stage.
Mengting Hu, Mengting Hu, Dan Zhang, Dan Zhang, Wentao Du, Wentao Du, Huijuan Tian, Huijuan Tian, Ying Hao, Ying Hao, Shuqi Ding, Shuqi Ding, Kaizhi Yang, Kaizhi Yang, Ruohang Xu, Ruohang Xu, Lei Zhang, Lei Zhang   +17 more
doaj   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Identification of Cold-Tolerant Breeding Lines by Quantitative Trait Loci Associated with Cold Tolerance in Rice

, 2012
Low temperature or cold stress is one of the major abiotic stresses limiting rice (Oryza sativa L.) production and productivity in the temperate rice growing regions as well as in tropical high lands worldwide.
Suh, J.P., Kim, S. M., Jena, K. K., Yang, C. I., Kim, Y.G.   +4 more
core   +1 more source

Natural variation of CTB5 confers cold adaptation in plateau japonica rice

Nature Communications
During cold acclimation in high-latitude and high-altitude regions, japonica rice develops enhanced cold tolerance, but the underlying genetic basis remains unclear.
Haifeng Guo, Shilei Gao, Huahui Li, Jiazhen Yang, Jin Li, Yunsong Gu, Qijin Lou, Runbin Su, Wei Ye, Andong Zou, Yulong Wang, Xingming Sun, Zhanying Zhang, Hongliang Zhang, Yawen Zeng, Pingrong Yuan, Youliang Peng, Zichao Li, Jinjie Li   +18 more
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

The reproductive cost of Drosophila melanogaster : effects on cold tolerance

, 2022
International audienceIn order to maintain their survival, species often make trade-offs between survival and reproduction, often resulting in reduced reproduction.
Colinet, Hervé, Gout, Romane
core  

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Cold Stress Responses of Different Genotypes of Miscanthus Assessed by Relative Electrical Conductivity and LT₅₀

Plants
We aim to provide a theoretical basis for improving the cold tolerance of Miscanthus spp., a widely recognized C4 perennial bioenergy crop, and extending its application in the industry.
Ning Peng, Songtao Guo, Yanmei Tang, Shicheng Li, Trang Pham, Xianyan Kuang, Zili Yi, Liang Xiao   +7 more
doaj   +1 more source