Results 151 to 160 of about 41,310 (264)

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

Early infliximab levels and clearance predict outcomes in acute severe ulcerative colitis. [PDF]

Transl Gastroenterol Hepatol
Al Hayek M, Elhadi M.
europepmc   +1 more source

The rs10781468 Genetic Polymorphism of the Gαq (GNAQ) Gene Is Associated With Responsiveness to Opioid Analgesics in Patients With Postoperative and Cancer Pain: An Exploratory Study

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
In our exploratory hypothesis‐generating study using patients with postoperative pain and cancer pain, for rs10781468 in the GNAQ gene, the minor allele was associated with reduced opioid consumption and an increased pain threshold. ABSTRACT Background G protein–coupled receptors, the largest class of cell surface receptors, are ubiquitously expressed ...
Hiroaki Owada, Daisuke Nishizawa, Tsutomu Mieda, Miki Tsujita, Hideyuki Nakagawa, Shigeki Yamaguchi, Rikuhei Tsuchida, Yaeko Yokoshima, Akira Kitamura, Masakazu Hayashida, Ken‐ichi Fukuda, Tatsuya Ichinohe, Kazutaka Ikeda, Makoto Kurano, Masahiko Sumitani, Kanji Uchida   +15 more
wiley   +1 more source

Functional vascular preservation during laparoscopic segmental left colectomy - Selective arterial ligation with preservation of the inferior mesenteric vein-A video vignette. [PDF]

Colorectal Dis
Viola Malet M, Laurini M, Durán F, Brito N, Domínguez Corbo F, Haro C, Viola Bartesaghi S.   +6 more
europepmc   +1 more source

The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Synergistic “Double Brake” Model on the Spinal Defecation Center in Clozapine‐Induced Constipation. Real‐world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and maintaining gut microbiota homeostasis prevents fatal Ogilvie's syndrome.
Takahiko Nagamine
wiley   +1 more source

Comparative Outcomes of Open, Laparoscopic, and Robotic Right Colectomy for Colon Cancer: Postoperative Recovery, Surgical Quality, and 3-Year Survival-A Monocentric Retrospective Study. [PDF]

Cancers (Basel)
Nowakowski K, Wesselmann L, Leitz M, Nimczewski F, Hoyer A, Baginski K, Hiller W, Hoeppner J, Madarasz Z.   +8 more
europepmc   +1 more source

Disease‐Intrinsic Organising Pneumonia During Biomarker‐Confirmed Ulcerative Colitis Remission

Respirology Case Reports, Volume 14, Issue 9, September 2026.
Organising pneumonia (OP) can occur as a disease‐intrinsic extraintestinal manifestation of ulcerative colitis (UC) during biochemical remission. Drug‐induced aetiology must be systematically excluded before attributing OP to UC. Cryobiopsy‐based ILD diagnoses require expert pathology review when treatment decisions are consequential, as the ...
Rahaf A. Jereisat, Nawras Ibrahim, Maher Dahdel   +2 more
wiley   +1 more source

A Case of Synchronous Laparoscopic Surgery for Sigmoid Colon Cancer Inaccessible by Colonoscopy and Left Adrenal Pheochromocytoma. [PDF]

Case Rep Surg
Tsubokawa Y, Kato T.
europepmc   +1 more source

Association Between Bowel Urgency and Intestinal Ultrasound Parameters in Ulcerative Colitis: Insights Into Transmural Inflammation and Symptom Pathophysiology

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Background Bowel urgency (BU) is a key symptom of ulcerative colitis (UC), often impairing the quality of life. This study aimed to identify intestinal ultrasound parameters associated with BU, given that UC may also have transmural involvement, and compare these with endoscopic activity and biomarkers.
Kanade Serizawa, Shintaro Sagami, Satoko Umeda, Kunio Asonuma, Moeko Komatsu, Shunsuke Shibui, Masa Maeda, Akira Nogami, Ryo Karashima, Masaru Nakano, Ichiro Maeda, Toshifumi Hibi, Chika Kusano, Taku Kobayashi   +13 more
wiley   +1 more source

The Unfinished Journey After Major Surgery: Interhospital Transfer and Care Fragmentation

World Journal of Surgery, Volume 50, Issue 9, Page 2565-2573, September 2026.
Interhospital transfer (IHTR) is commonly used to access specialized surgical care, yet post‐discharge readmission destination among transferred surgical patients remains poorly characterized. Therefore, the association of IHTR and hospital transfer burden with care fragmentation after major surgery was evaluated. IHTR was strongly associated with care
Rida Ejaz, Qaidar Alizai, Lorenza Arena, Kizuki Yuza, Charalampos M. Charalampous, Abdulaziz Elemosho, Timothy M. Pawlik   +6 more
wiley   +1 more source