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Nature Reviews Disease Primers, 2020 Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown aetiology affecting the colon and rectum. Multiple factors, such as genetic background, environmental and luminal factors, and mucosal immune dysregulation, have been suggested to contribute to UC pathogenesis.
Taku Kobayashi +9 more
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Ulcerative Colitis in Adults: A Review.
Journal of the American Medical Association (JAMA), 2023Importance Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower life expectancy and are at increased risk for colectomy and colorectal ...
B. Gros, G. Kaplan
semanticscholar +1 more source
New Therapeutics for Ulcerative Colitis.
Annual Review of Medicine, 2021Ulcerative colitis (UC) is a relapsing and remitting inflammatory disease of the colon with a variable course. Despite advances in treatment, only approximately 40% of patients achieve clinical remission at the end of a year, prompting the exploration of
R. Hirten, B. Sands
semanticscholar +1 more source
The Lancet, 2023
Ulcerative colitis is a lifelong inflammatory disease affecting the rectum and colon to a variable extent. In 2023, the prevalence of ulcerative colitis was estimated to be 5 million cases around the world, and the incidence is increasing worldwide. Ulcerative colitis is thought to occur in people with a genetic predisposition following environmental ...
Le Berre, Catherine +2 more
openaire +3 more sources
Ulcerative colitis is a lifelong inflammatory disease affecting the rectum and colon to a variable extent. In 2023, the prevalence of ulcerative colitis was estimated to be 5 million cases around the world, and the incidence is increasing worldwide. Ulcerative colitis is thought to occur in people with a genetic predisposition following environmental ...
Le Berre, Catherine +2 more
openaire +3 more sources
The Lancet, 2002
Ulcerative colitis is a chronic inflammatory disease of the rectum and colon. Results from many studies in people and animals of intestinal inflammation suggest that ulcerative colitis results from environmental factors triggering a loss of tolerance for normal intestinal flora in genetically susceptible individuals.
Richard J, Farrell, Mark A, Peppercorn
openaire +3 more sources
Ulcerative colitis is a chronic inflammatory disease of the rectum and colon. Results from many studies in people and animals of intestinal inflammation suggest that ulcerative colitis results from environmental factors triggering a loss of tolerance for normal intestinal flora in genetically susceptible individuals.
Richard J, Farrell, Mark A, Peppercorn
openaire +3 more sources
Gut microbiota in ulcerative colitis: insights on pathogenesis and treatment
Journal of Digestive Diseases, 2020Gut microbiota constitute the largest reservoir of the human microbiome and are an abundant and stable ecosystem—based on its diversity, complexity, redundancy, and host interactions This ecosystem is indispensable for human development and health.
Xiao-yan Guo, Xin Liu, J. Hao
semanticscholar +1 more source
Journal of Crohn's & Colitis, 2020
BACKGROUND Gastrointestinal ultrasound is useful in the assessment of patients with Crohn's disease, but its application in ulcerative colitis is less well established.
Rebecca L Smith +4 more
semanticscholar +1 more source
BACKGROUND Gastrointestinal ultrasound is useful in the assessment of patients with Crohn's disease, but its application in ulcerative colitis is less well established.
Rebecca L Smith +4 more
semanticscholar +1 more source