What's New? Integrins are critical mediators of cell adhesion and migration and have been implicated in cancer progression. Here, the authors show that endothelial cells in target organs of colorectal cancer metastasis express fibronectin, and that colorectal cancer tumour cells can bind fibronectin through integrin β6. This interaction is resistant to
Chiara Van Passen+16 more
wiley +1 more source
PTEN Inactivation in Mouse Colonic Epithelial Cells Curtails DSS-Induced Colitis and Accelerates Recovery. [PDF]
Kotelevets L+5 more
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Microbial keystone species and gut microbiota composition are highly variable during the pathological development of the behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease (AD). Age stratification reveals stage‐specific gut microbial signatures in AD‐related BPSD.
Fu‐You Su+7 more
wiley +1 more source
The Non-Peptide MAS-R Agonist AVE0991 Alleviates Colitis Severity in Mice and Exhibits an Additive Effect with Azathioprine. [PDF]
Khajah MA, Hawai S, Barakat A.
europepmc +1 more source
Saliva MicroAge is a machine learning‐based model designed to estimate biological age and assess health status using globally sourced salivary microbiome data. Trained on 4532 healthy samples, the model achieves high accuracy in predicting chronological age and captures health‐related deviations (MicroAgeGap) in various diseases.
Tiansong Xu+13 more
wiley +1 more source
Biotin/sulfasalazine combination therapy alleviates acetic acid-induced ulcerative colitis in rats via modulation of S1PR1/NF-κB/IL-23/STAT3/COX-2 axis. [PDF]
Helmy SA+3 more
europepmc +1 more source
Microplastic‐induced gut microbial enrichment was dominated by bacteria within Eubacteriales, correlated with the virome, and accompanied by colitis. The polyamine synthetic pathway was activated to maintain glutathionylspermidine homeostasis, concurrent with decreases in pathways involved in the production of energy and reactive oxygen species under ...
Guozhu Ye+6 more
wiley +1 more source
Curcumin Ameliorates DSS-Induced Colitis in Mice Through Modulation of Gut Microbiota and Metabolites. [PDF]
Yi C+6 more
europepmc +1 more source
Cytomegalovirus Proctitis Mimicking Inflammatory Bowel Disease in an Immunocompetent Elderly Patient: A Diagnostic Challenge. [PDF]
Hagen R, Da Cunha T, Potashinsky A.
europepmc +1 more source
Endocytoscopy in real-time assessment of histological and endoscopic activity in ulcerative colitis. [PDF]
Chaemsupaphan T+4 more
europepmc +1 more source