Results 261 to 270 of about 6,929,436 (348)

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, Mariia Moshkova, Iuliia Pilipenko, David W. Cescon, Eugenia Kumacheva   +7 more
wiley   +1 more source

Healthcare providers' experiences of community-based collaborative care for serious mental illness: a qualitative study in two integrated clinics in South Africa. [PDF]

Glob Ment Health (Camb)
Abdulla S, Robertson L, Kramer S, Goudge J.   +3 more
europepmc   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Development and Implementation of a Self-Management Intervention Program for Patients with Esophageal and Gastric Varices Secondary to Liver Cirrhosis Under Collaborative Care. [PDF]

Int J Gen Med
Li M, Xie XE, Qin X, Wu T, Bian ZL.
europepmc   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Integrated Collaborative Care for Youths With Mental Health and Substance Use Challenges: A Randomized Clinical Trial.

JAMA Netw Open
Henderson J, Szatmari P, Cleverley K, Ma C, Hawke LD, Cheung A, Relihan J, Dixon M, Quinlan-Davidson M, Moretti M, de Oliveira C, Lee A, Courtney DB, O'Brien D, McDonald H, Lemke K, Pignatiello T, Monga S, Kozloff N, Solomon L, Andrade BF, Barwick M, Charach A, Courey L, Darnay K, Kurdyak P, Lin E, Shan D.   +27 more
europepmc   +1 more source

A Pre-Adoption Assessment of a Collaborative Care Approach to Dental-Fear Treatment. [PDF]

Oral (Basel)
Daly KA, Heyman RE, Drew AL, Smith Slep AM, Bubis R, Lee JJ, Pearce VVV, Jones R, Ruggiero M, Wolff MS.   +9 more
europepmc   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Towards collaborative care for severe and enduring Anorexia Nervosa - a mixed-method approach. [PDF]

J Eat Disord
van den Eijnde-Damen IMC, Maas J, Burger P, Bodde NMG, Simeunovic-Ostojic M.   +4 more
europepmc   +1 more source