Results 41 to 50 of about 548,790 (284)

S’adapter à l’éthique de la différenciation en évaluation des apprentissages : une analyse de l’expérience des enseignants formés à l’étranger au Québec

Mesure et Évaluation en Éducation, 2022
Dans la dernière décennie, l’école québécoise a accueilli un nombre important d’enseignants formés à l’étranger (MEES, 2018). Les recherches sur leur savoir-évaluer montrent que, pour les enseignants qui s’habituent aux normes et aux valeurs de la ...
Serigne Ben Moustapha Diédhiou, Dan Thanh Duong Thi, Arianne Robichaud   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Collaborative research: Accomplishments & potential [PDF]

Environmental Health, 2008
Although a substantial part of scientific research is collaborative and increasing globalization will probably lead to its increase, very few studies actually investigate the advantages, disadvantages, experiences and lessons learned from collaboration.
openaire   +5 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Methods and approach to the interdisciplinary and cross-cultural Arctic Alaska Salmon Workshop: critical self-reflections from fisheries scientists

Arctic Science
Redistribution and shifting habitat envelopes are impacting organisms across many taxa, which in turn are impacting Indigenous ways of life. In Arctic Alaska, Pacific salmon are known to have occurred for at least a century, but in recent years appear to
Elizabeth D. Lindley, Peter A.H. Westley
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Avaliação apreciativa de um Núcleo de Prática Jurídica

Revista Direito GV
Resumo Este artigo busca fazer uma avaliação apreciativa do Núcleo de Prática Jurídica da Faculdade de Direito do Recife (NPJ/FDR). Conforme o paradigma apreciativo utilizado, o referencial conjuga teoria, método e ação de forma alinhada com o modelo de ...
Rezilda Rodrigues Oliveira, Francinete Paula Alves Pereira   +1 more
doaj   +1 more source