Results 81 to 90 of about 2,318,654 (287)
Contextes et Didactiques, 2020 Interested by the question of the developpement of teachers’ skills, we will present an in-service training designed for CLIL teachers. We will build our analysis by refering to studies developped both in the field of CLIL teaching and of teachers ...
Myriam Abou-Samra
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Safe environments for innovation: developing a new multidisciplinary masters programme [PDF]
, 2010 This paper outlines the research and resulting curriculum design activities conducted as a collaborative venture between Northumbria University’s School of Design, School of Computing, Engineering and Information Sciences and Newcastle Business School ...
Bailey, Mark, Smith, Neil
core
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Information technology as boundary object for transformational learning [PDF]
, 2009 Collaborative work is considered as a way to improve productivity and value generation in construction. However, recent research demonstrates that socio-cognitive factors related to fragmentation of specialized knowledge may hinder team performance. New
Forgues, Daniel +2 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FACETSIn this paper, we argue that Indigenous data sovereignty (IDS) is vital for addressing threats to ecosystems, as well as for Indigenous Peoples re-establishing and maintaining sovereignty over their territories. Indigenous knowledge-holders face pressure
S.E. Cannon +26 more
doaj +1 more source
A novel approach to collaborative product development in the medical-equipment industry [PDF]
, 2013 In this study, we summarise the requirements for collaborative product development based on our investigation of the differences in the resources and tools that are needed for the various stages of collaborative product development and the needs of ...
Chien-Lung, Hsu, Tseng, Kevin C
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Transdisciplinarity at the Crossroads: Nurturing Individual and Collective Learning
Technology Innovation Management Review, 2018 Practitioners of transdisciplinary inquiry, which we define to include research, learning, collaboration, and action, encounter innumerable tensions. Some tensions are universal, while others are unique to that particular inquiry at that point in time ...
Chris Riedy +3 more
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