Results 41 to 50 of about 277,190 (298)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

A clustered regularly interspaced palindromic repeat‐Cas12a‐based assay for rapid dengue virus monitoring in mosquito and clinical samples facilitating global collaborative surveillance and risk assessment to block dengue spreading

Interdisciplinary Medicine
Dengue fever, an acute Aedes‐borne infectious disease caused by the dengue virus (DENV), is a substantial global health challenge, necessitating the development of swift and effective surveillance methodologies.
Xiang Guo, Minling Hu, Ying Lu, Xiaohua Liu, Haiyang Chen, Xiaoqing Zhang, Liu Ge, Ziyao Li, Yuji Wang, Qing He, Shu Zeng, Wenwen Ren, Lingzhai Zhao, Zhiqiang Peng, Wushen Chen, Chunmei Wang, Qingming Kong, Shaohong Lu, Fuchun Zhang, Lei Luo, Hua Li, Xiao‐Guang Chen, Xiaohong Zhou   +22 more
doaj   +1 more source

Empowering public health: building advanced molecular surveillance in resource-limited settings through collaboration and capacity-building

Frontiers in Health Services
The rapid detection and continuous surveillance of infectious diseases are important components of an effective public health response. However, establishing advanced molecular surveillance systems, crucial for monitoring and mitigating pandemics, poses ...
Hornel Koudokpon, Boris Lègba, Kevin Sintondji, Islamiath Kissira, Arielle Kounou, Ibrehima Guindo, Kléma Marcel Koné, Mahamadou Abdou, Amadou Koné, Claire Sambou, Honoré Bankolé, Anges Yadouleton, Victorien Dougnon   +12 more
doaj   +1 more source

Key factors for sustainability of regional animal health networks: CaribVET example [PDF]

, 2012
CaribVET is a collaborative network of veterinary services, research institutes and regional/international organizations whose objective is to improve animal and veterinary public health in the Caribbean. Set up on a bottom-up process about 15 years ago,
Faverjon, Céline, Gongora, Victor, Kackshaw, K., Kalloo, Margaret, Lefrançois, Thierry, Pradel, Jennifer, Shaw, J.   +6 more
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Age, sex, income, sociodemographic and health system inequalities in the global burden of high systolic blood pressure: an analysis of the Global Burden of Disease Study 2021

BMJ Open
Objectives To examine the global and regional trends in disparities of high systolic blood pressure (HSBP) burden between 1990 and 2021 by age, sex, sociodemographic index and health systems’ performance.Design Systematic analysis.Setting Global ...
Hamid Sharifi, Seyed Aria Nejadghaderi, Azin Kadkhodamanesh, Mohammad-Mahdi Bastan, Meraj Sharifi   +4 more
doaj   +1 more source

Antibiotic resistance in Vietnam: moving towards a One Health surveillance system

BMC Public Health, 2018
Background The international community strongly advocates the implementation of multi-sectoral surveillance policies for an effective approach to antibiotic resistance, in line with the One Health concept.
Marion Bordier, Aurelie Binot, Quentin Pauchard, Dien Thi Nguyen, Thanh Ngo Trung, Nicolas Fortané, Flavie Luce Goutard   +6 more
doaj   +1 more source

Node discovery in a networked organization

, 2009
In this paper, I present a method to solve a node discovery problem in a networked organization. Covert nodes refer to the nodes which are not observable directly.
Maeno, Yoshiharu
core   +1 more source