Results 11 to 20 of about 1,105,102 (308)

Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation

open access: yesAntioxidants, 2020
Antioxidants are molecules that delay or inhibit the oxidation of other molecules. Its use significantly increased in recent years in the diet of people. Natural antioxidants are replacing the use of synthetic antioxidant ingredients due to their safety,
Gabriel Aguirre-Cruz   +4 more
doaj   +1 more source

Tofacitinib versus tocilizumab in the treatment of biological-naïve or previous biological-failure patients with methotrexate-refractory active rheumatoid arthritis

open access: yesRMD Open, 2021
Objectives To compare effectiveness between tofacitinib and tocilizumab treatments for biological disease-modifying antirheumatic drug (bDMARD)-naïve patients or previous bDMARD-failure patients with active rheumatoid arthritis (RA) refractory to ...
Yukitaka Ueki   +3 more
doaj   +1 more source

Structure-mechanics relationships of collagen fibrils in the Osteogenesis Imperfecta Mouse model [PDF]

open access: yes, 2015
The collagen molecule, which is the building block of collagen fibrils, is a triple helix of two α1(I) chains and one α2(I) chain. However, in the severe mouse model of osteogenesis imperfecta (OIM), deletion of the COL1A2 gene results in the ...
Andriotis, OG   +7 more
core   +4 more sources

Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides. [PDF]

open access: yes, 2019
Collagen is the most widespread extracellular matrix (ECM) protein in the body and is important in maintaining the functionality of organs and tissues.
Goldbloom-Helzner, Leora   +2 more
core   +1 more source

Understanding the viscoelastic behavior of collagen matrices through relaxation time distribution spectrum [PDF]

open access: yes, 2013
This study aims to provide understanding of the macroscopic viscoelastic behavior of collagen matrices through studying the relaxation time distribution spectrum obtained from stress relaxation tests.
Li, Haiyue, Xu, Bin, Zhang, Yanhang
core   +1 more source

The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila [PDF]

open access: yes, 2018
Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure.
Hartley, Paul S.   +3 more
core   +1 more source

The first case of thrombocytopenia, anasarca, fever, renal impairment or reticulin fibrosis, and organomegaly (TAFRO) syndrome with unilateral adrenal necrosis: a case report

open access: yesJournal of Medical Case Reports, 2018
Background TAFRO syndrome, which was first reported in 2010 in Japan, is a relatively rare disease characterized by thrombocytopenia, anasarca, fever, renal impairment, reticulin fibrosis, and organomegaly.
Yu Fujiwara   +3 more
doaj   +1 more source

Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix [PDF]

open access: yes, 2015
Despite the crucial role of extracellular matrix (ECM) in directing cell fate in healthy and diseased tissues--particularly in development, wound healing, tissue regeneration and cancer--the mechanisms that direct the assembly and regulate hierarchical ...
Gourdon, Delphine   +7 more
core   +2 more sources

Collagens and collagen-related diseases

open access: yesAnnals of Medicine, 2001
The collagen superfamily of proteins plays a dominant role in maintaining the integrity of various tissues and also has a number of other important functions. The superfamily now includes more than 20 collagen types with altogether at least 38 distinct polypeptide chains, and more than 15 additional proteins that have collagen-like domains.
J, Myllyharju, K I, Kivirikko
openaire   +2 more sources

Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair [PDF]

open access: yes, 2000
We deveiop a novel mathematical model for collagen deposition and alignment during dermal wound healing. We focus on the interactions between fibroblasts, modelled as discrete entities, and a continuous extracellular matrix composed of collagen and a ...
Dallon, J. C.   +3 more
core   +1 more source

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