Results 91 to 100 of about 437,388 (294)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Organization, density, and content of collagen in the body wall of sea cucumbers Acaudina rosettis and Phyllophorus sp.

Aquaculture and Fisheries
Marine collagen has been known to have lower immunogenicity compared to bovine collagen. The primary component in the body wall of sea cucumbers is collagen.
Nithasya Nabilla, Imarotus Shofiyah, Sugiharto, Dita Alvitasari, Sri Sumarsih, Firas Khaleyla, Ismiliana Wirawati, Dwi Winarni   +7 more
doaj   +1 more source

Impact of the use of Ethanolic Extract of Propolis, Flavonoid and Non-Flavonoid Propolis for Direct Pulp Capping in Collagen Type I Density

Brazilian Journal of Oral Sciences, 2017
Aim: To analysis collagen type I density on inflamed rat dental pulp after capping with propolis. Methods: Flavonoid and non-flavonoid substances were purified from propolis.
Ardo Sabir, Latief Mooduto, Cahyono Kaelan, Sherly Horax   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Confined compression of collagen hydrogels [PDF]

, 2013
Reconstituted collagen hydrogels are often used for in vitro studies of cell-matrix interaction and as scaffolds for tissue engineering. Understanding the mechanical and transport behaviours of collagen hydrogels is therefore extremely important, albeit ...
Busby, Grahame A., Grant, M. Helen, MacKay, Simon P., Riches, Philip E.   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Exosomes from Hypoxic Mesenchymal Stem Cells Enhance TGF-β Expression and Promote Collagen Regeneration in Wistar Rats with Collagen Loss

MCBS (Molecular and Cellular Biomedical Sciences)
Background: Ultraviolet B (UVB) exposure triggers reactive oxygen species (ROS) formation, inhibits procollagen synthesis via the transforming growth factor-beta (TGF-β)/Smad pathway, and leads to collagen loss.
Ade Ifalliah Putri Kusumawardani, Prasetyowati Subchan, Titiek Sumarawati, Eko Setiawan   +3 more
doaj   +1 more source

The effect of advanced glycation endproduct accumulation on bone [PDF]

, 2017
Diabetes is associated with increased fracture risk, which leads to increased morbidity and eventual mortality with a substantial financial burden.
Van Vliet, Miranda
core  

Elastica-based strain energy functions for soft biological tissue

, 2007
Continuum strain energy functions are developed for soft biological tissues that possess long fibrillar components. The treatment is based on the model of an elastica, which is our fine scale model, and is homogenized in a simple fashion to obtain a ...
Garikipati, K., Göktepe, S., Miehe, C.
core   +4 more sources

The role of nailfold capillaroscopy in interstitial lung diseases - Can it differentiate idiopathic cases from collagen tissue disease associated interstitial lung diseases? [PDF]

, 2015
Introduction: Nailfold capillaroscopy (NFC) is a non-invasive diagnostic test that is mostly used for early diagnosis of collagen tissue diseases (CTDs). We aimed to evaluate whether NFC findings could be a clue for discriminating idiopathic interstitial
Altınışık, Göksel, Balkarli, A., Çakmakçi Karadoğan, D., Çobankara, Veli, Önal, Özgür   +4 more
core   +1 more source