Results 61 to 70 of about 437,388 (294)

Active wetting of epithelial tissues

, 2019
Development, regeneration and cancer involve drastic transitions in tissue morphology. In analogy with the behavior of inert fluids, some of these transitions have been interpreted as wetting transitions.
A Ravasio, AF Mertz, AF Mertz, AG Clark, AMJ Edwards, AR Harris, B Smeets, B Wallmeyer, C Blanch-Mercader, C Blanch-Mercader, C Cortina, Carles Blanch-Mercader, Carlos Pérez-González, D Bonn, D Gonzalez-Rodriguez, D Oriola, D Sarrió, DK Vig, DT Tambe, DT Tambe, E Bazellières, Elsa Bazellieres, F Jülicher, G Beaune, G Beaune, H Morita, I Muhamed, I Rodriguez-Hernandez, J Notbohm, J Paredes, J Prost, Jaume Casademunt, JL Ouderkirk, K Kruse, KA Paschos, L Casares, M Behrndt, M Deforet, Manuel Gómez-González, MC Marchetti, MH Köpf, O Chepizhko, P Campinho, P Friedl, P Gennes de, P Lee, P Lee, P Lu, PL Ryan, Ricard Alert, S Banerjee, S Douezan, S Douezan, S Douezan, S Garcia, S Kaliman, S Yabunaka, T Lecuit, TB Saw, Tomasz Kolodziej, TV Stirbat, US Schwarz, X Serra-Picamal, X Trepat, Xavier Trepat   +64 more
core   +3 more sources

The biomechanics of amnion rupture: an X-ray diffraction study [PDF]

, 2007
Pre-term birth is the leading cause of perinatal and neonatal mortality, 40% of which are attributed to the pre-term premature rupture of amnion. Rupture of amnion is thought to be associated with a corresponding decrease in the extracellular collagen ...
Andrew Quantock, Andy Hopkinson, Che J. Connon, CJ Connon, CR Worthington, DWL Hukins, EL Stuart, GL Bourne, GL Clark, H Krenchel, H Lei, J Aplin, James Doutch, JH Venable, JM Goodfellow, Joseph Orgel, JT Halaburt, Keith M. Meek, KM Meek, L Paavola, MJ Keirse, ML Watson, MN Bou-Resli, Naoto Yagi, NS Al-Zaid, R Aspden, R Lewis, RA Farrell, RL Goldenberg, RM Moore, S Parry, Takahiro Nakamura, TM Malak   +32 more
core   +3 more sources

Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]

, 2020
Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A., Parmentier, Laurens, Riffault, Mathieu   +2 more
core   +1 more source

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]

, 2017
Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu, Guillaume Mabilleau, Iepsen, Iepsen, Marie Pereira   +4 more
core   +5 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Effect of 5% sildenafil citrate gel application on collagen density and epithelial thickness in secondary healing of the palate excision wound- An In-Vivo study on Wistar rats

Journal of Orofacial Sciences
Introduction: Palatoplasty is a treatment to repair a cleft palate, the most common congenital deformity in infants. Some palatoplasty techniques result in exposed bone on the lateral palate that heals with secondary healing and increases scar tissue ...
Gilang Jati Pamungkas, Cahya Yustisia Hasan, Pingky Krisna Arindra   +2 more
doaj   +1 more source

Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cells [PDF]

Environmental Toxicology and Pharmacology, 2015
Breast density, where collagen I is the dominant component, is a significant breast cancer risk factor. Cell surface integrins interact with collagen, activate focal adhesion kinase (FAK), and downstream cell signals associated with xenobiotics (AhR, ARNT) and hypoxia (HIF-1α, ARNT).
Colleen S, Curran, Esteban R, Carrillo, Suzanne M, Ponik, Patricia J, Keely   +3 more
openaire   +2 more sources

Collagen Fibril Density Modulates Macrophage Activation and Cellular Functions during Tissue Repair [PDF]

Bioengineering, 2020
Monocytes circulate in the bloodstream, extravasate into the tissue and differentiate into specific macrophage phenotypes to fulfill the immunological needs of tissues. During the tissue repair process, tissue density transits from loose to dense tissue.
Jiranuwat Sapudom, Walaa Kamal E. Mohamed, Anna Garcia-Sabaté, Aseel Alatoom, Shaza Karaman, Nikhil Mahtani, Jeremy C. M. Teo   +6 more
openaire   +4 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The effect of saffron serum on collagen density, inflammatory gene expression, and autophagy in UVB-exposed Wistar rats

Universa Medicina
Background Skin aging is a complex biological phenomenon influenced by intrinsic and extrinsic factors. Photoaging can be prevented by applying phytochemicals that have sun-protective properties.
Chitra Octavia, Julia Windi Gunadi, Oeij Anindita Adhika, Lani Ishak, Diana Krisanti Jasaputra, Alexandrina Everdine Rosali, Ardo Sanjaya   +6 more
doaj   +1 more source