Zhilong Huoxue Tongyu capsule inhibits hypertensive myocardial fibrosis via balancing TGF-β1/Smad3/Erbb4-IR/miR-29b pathway. [PDF]
Liu Q+10 more
europepmc +1 more source
Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim+7 more
wiley +1 more source
Targeted incorporation of collagen IV to the basement membrane: A step forward for developing extracellular protein therapies. [PDF]
Pokidysheva EN+4 more
europepmc +1 more source
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu+9 more
wiley +1 more source
High-content Image-based Drug Testing of Patients' Primary Fibroblasts Reveals Potential New Treatment Options for Localized Scleroderma. [PDF]
Mähönen K+10 more
europepmc +1 more source
Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritis [PDF]
Ian K. Campbell+2 more
openalex +1 more source
Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley +1 more source
Decreased Protein C Activation Is Associated With Abnormal Collagen Turnover in the Intraalveolar Space of Patients With Interstitial Lung Disease [PDF]
Hiroki Yasui+10 more
openalex +1 more source