Results 31 to 40 of about 371,953 (265)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Intraoral lobular capillary hemangioma in the esthetic zone

Journal of Indian Society of Periodontology
Lobular capillary hemangioma (LCH), previously known as pyogenic granuloma, is a benign vascular lesion commonly affecting the oral cavity. Despite its misleading name, LCH represents a reactive hyperplastic proliferation of capillaries, often triggered ...
Shubham Sareen, Lata Goyal, Shipra Gupta, Stadialam Kharbuli   +3 more
doaj   +1 more source

Production, Characterization and Biocompatibility of Marine Collagen Matrices from an Alternative and Sustainable Source: The Sea Urchin Paracentrotus lividus

Marine Drugs, 2014
Collagen has become a key-molecule in cell culture studies and in the tissue engineering field. Industrially, the principal sources of collagen are calf skin and bones which, however, could be associated to risks of serious disease transmission. In fact,
Cristiano Di Benedetto, Alice Barbaglio, Tiziana Martinello, Valentina Alongi, Dario Fassini, Emanuele Cullorà, Marco Patruno, Francesco Bonasoro, Mario Adolfo Barbosa, Maria Daniela Candia Carnevali, Michela Sugni   +10 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Nursing-led management of a complex traumatic wound in an outpatient setting: A case study [PDF]

Journal of Nursing Reports in Clinical Practice
Effective wound management is a fundamental part of nursing practice and plays a critical role in promoting healing, preventing complications, and improving patient outcomes.
Migdrey M. Falcon Martinez, Mizudes M. La O Nodarse, Idaelvis M. Danger Correoso, Meiser Alvarez Jimenez, Boris Luis Garcia Freire, Ernesto L. Fleites Santisteban   +5 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Baseline-Dependent Biological Response to Peri-Implant Soft Tissue Augmentation: A Secondary Analysis of a Randomized Clinical Trial

Journal of Functional Biomaterials
Objectives: Clinical outcomes of peri-implant soft tissue augmentation remain variable, and baseline-associated factors of treatment response are poorly understood.
Jakub Hadzik, Paweł Kubasiewicz-Ross, Umberto Romeo, Krzysztof Kujawa, Nicola Alberto Valente, Marzena Dominiak   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Collagens and proteoglycans of the corneal extracellular matrix [PDF]

Brazilian Journal of Medical and Biological Research, 2003
The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with endothelium.
openaire   +5 more sources

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source