Results 121 to 130 of about 646,289 (307)
JCI InsightDupuytren’s disease is a common fibroproliferative disease of the palmar fascia of the hand, with advanced cases treated surgically. Anti-TNF injection has undergone phase 2 trials and may be effective in slowing early-stage disease progression.
Kate Williamson +15 more
doaj +1 more source
Long-term histological comparison between near-infrared irradiated skin and scar tissues
Clinical, Cosmetic and Investigational Dermatology, 2010 Yohei Tanaka1,2, Kiyoshi Matsuo1, Shunsuke Yuzuriha11Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, Matsumoto, Japan; 2Clinica Tanaka Plastic and Reconstructive Surgery and Anti-aging Center, Matsumoto ...
Yohei Tanaka +2 more
doaj
Parallel 3D Bioprinting on SLIPS‐Microarrays
Advanced Functional Materials, EarlyView.This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg +3 more
wiley +1 more source
The effects of cross linking on collagen type 1 nanostructure and nanostructural response to uniaxial tension : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Engineering at Massey University, Manawatu, New Zealand [PDF]
, 2016 Reproduced by permission of The Royal Society of Chemistry: Kayed, H. R., Sizeland, K. H., Kirby, N., Hawley, A., Mudie, S. T., & Haverkamp, R. G. (2015). Collagen cross linking and fibril alignment in pericardium. RSC Advances, 5, 3611-3618.
Kayed, Hanan
core
Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Quantitative real-time RT-PCR determining extracellular matrix protein expression in osteogenesis imperfecta murine (oim) thoracic aortas [abstract] [PDF]
, 2004 only availableFaculty Mentor: Dr. Charlotte Phillips, Biochemistry and Child HealthPrimary components of the thoracic aorta critical for tissue integrity are collagen and elastin. Collagen, a rod-like protein contributes to aortic strength and stiffness,
Wirth, David
core
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
Advanced Functional Materials, EarlyView.A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source
Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel
Advanced Functional Materials, EarlyView.This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar +5 more
wiley +1 more source
Glomerulosclerosis in the Col1a2-deficient mouse model : homotrimer pathogenesis and MMP expression [PDF]
Title from PDF of title page (University of Missouri--Columbia, viewed on Feb. 20, 2010).The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the ...
Roberts-Pilgrim, Anna M., 1977-
core +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source