Results 51 to 60 of about 387,585 (164)
Lung remodeling in a mouse model of asthma involves a balance between TGF-β1 and BMP-7.
PLoS ONE, 2014 A key event in chronic allergic asthma is the TGF-β-induced activation of fibroblasts into α-SMA-positive myofibroblasts which synthesize type-I collagen. In the present study we investigated the effect of the anti-fibrotic molecule BMP-7 in asthma. Balb/
Camila Leindecker Stumm +5 more
doaj +1 more source
CosmeticsAging leads to a decline in skin function due to intrinsic factors (genetics, hormones) and extrinsic factors (sun exposure, pollutants). Type I collagen plays a vital role in maintaining skin integrity and elasticity.
Ofek Bar, Skaidra Valiukevičienė
doaj +1 more source
BiomedicinesOsteopontin (OPN) and osteoprotegerin (OPG) are glycoproteins that participate in the regulation of tissue biomineralization. The aim of the project is to verify the hypothesis that the content of OPN and OPG in the aorta walls increases with the ...
Aleksandra Kuzan +4 more
doaj +1 more source
AUTOIMMUNE ASPECTS OF COLLAGEN HOMEOSTASIS DISORDER IN UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA
Медицинская иммунология, 2014 . The levels of autoantibodies to collagen type I, II, III, IV and V were studied in blood plasma of 130 patients (18-32 years old) with undifferentiated connective tissue dysplasia, using immunoenzyme analysis.
A. V. Yagoda, N. N. Gladkikh
doaj +1 more source
JCI InsightDupuytren’s disease is a common fibroproliferative disease of the palmar fascia of the hand, with advanced cases treated surgically. Anti-TNF injection has undergone phase 2 trials and may be effective in slowing early-stage disease progression.
Kate Williamson +15 more
doaj +1 more source
Long-term histological comparison between near-infrared irradiated skin and scar tissues
Clinical, Cosmetic and Investigational Dermatology, 2010 Yohei Tanaka1,2, Kiyoshi Matsuo1, Shunsuke Yuzuriha11Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, Matsumoto, Japan; 2Clinica Tanaka Plastic and Reconstructive Surgery and Anti-aging Center, Matsumoto ...
Yohei Tanaka +2 more
doaj
CellsHeat shock protein 47 (HSP47), also known as SERPINH1, functions as a collagen-specific molecular chaperone protein essential for the formation and stabilization of the collagen triple helix. Here, we delved into the regulatory pathways governed by HSP47,
So Young Ham +6 more
doaj +1 more source
Scientific ReportsComprehensive information on the meniscus root microstructure is essential to exactly understand its physiological role and susceptibility to injury. We selected the ovine medial meniscus anterior root (MAR) as model to elucidate the intricate spatial ...
Marta Carretero-Hernández +4 more
doaj +1 more source
From Collagen Colour to Collagen Biology: An Integrated Framework for Dermal Remodelling Assessment
CosmeticsAge-related deterioration of the dermal extracellular matrix is driven primarily by fibroblast dysfunction, leading to loss of collagen integrity, elasticity, and structural support.
Francesco Marchetti +4 more
doaj +1 more source