Results 81 to 90 of about 646,289 (307)

The In Situ Supermolecular Structure of Type I Collagen [PDF]

open access: yesStructure, 2001
The proteins belonging to the collagen family are ubiquitous throughout the animal kingdom. The most abundant collagen, type I, readily forms fibrils that convey the principal mechanical support and structural organization in the extracellular matrix of connective tissues such as bone, skin, tendon, and vasculature.
Orgel, J P R O   +5 more
openaire   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Gold nanoparticles coated with collagen-I and their wound healing activity in human skin fibroblast cells

open access: yesHeliyon
The slow wound healing process has become a major health problem. Gold nanoparticles (AuNPs) have been used in various biomedical applications because of their unique properties.
Sasiprapa Poomrattanangoon   +1 more
doaj   +1 more source

Changes in the Type I Collagen mRNA Expression in the Isthmus During the Passage of Egg Through the Oviduct in Japanese Quail

open access: yesThe Journal of Poultry Science, 2003
Type I collagen is one of the major components contained in the eggshell membrane. The aim of this study was to determine whether the expression of type I collagen mRNA is changed during the passage of the egg through the oviduct in Japanese quail ...
Hiroki Ohashi   +2 more
doaj   +1 more source

Transdermal Delivery of Functional Collagen \u3cem\u3eVia\u3c/em\u3e Polyvinylpyrrolidone Microneedles [PDF]

open access: yes, 2015
Collagen makes up a large proportion of the human body, particularly the skin. As the body ages, collagen content decreases, resulting in wrinkled skin and decreased wound healing capabilities.
Inayathullah, Mohammed   +9 more
core   +1 more source

Comparative Effectiveness of Structural versus Regulatory Protein Gene Transfer on Articular Chondrocyte Matrix Gene Expression [PDF]

open access: yes, 2019
OBJECTIVE: The production of extracellular matrix is a necessary component of articular cartilage repair. Gene transfer is a promising method to improve matrix biosynthesis by articular chondrocytes.
Chan, Albert   +5 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Investigation of type I collagen deposition in the glomeruli of COL1A2 deficient mice [PDF]

open access: yes, 2004
only availableType I collagen is the most abundant structural protein in the body, playing a major role in the strength and integrity of connective tissues.
Brodeur, Amanda C., 1978-   +4 more
core  

The biocompatibility of titanium in a buffer solution: compared effects of a thin film of TiO2 deposited by MOCVD and of collagen deposited from a gel [PDF]

open access: yes, 2007
This study aims at evaluating the biocompatibility of titanium surfaces modified according two different ways: (i) deposition of a bio-inert, thin film of rutile TiO2 by chemical vapour deposition (MOCVD), and (ii) biochemical treatment with collagen gel,
Alain N. Gleizes   +37 more
core   +4 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

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