Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Does gravity induce wavefunction collapse? An examination of Penrose's conjecture [PDF]
, 2013 According to Penrose, the fundamental conflict between the superposition principle of quantum mechanics and the principle of general covariance of general relativity entails the existence of wavefunction collapse, e.g.
Gao, Shan, Shan Gao
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Physics of Collapse and Terminating Events [PDF]
, 1997 Various catastrophic phenomena, including the sawtooth, ELMs, High-beta collapse, etc., have been known in plasmas. The large scale deformation and transition take place abruptly, characterizing the spatio-temporal evolution of the plasma structure.
INOUE, Sanae, ITOH, Sanae -I.
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Quantum potential in bouncing dust collapse with a negative cosmological constant
Physics Letters B, 2021 In the functional Schrodinger formalism, we obtain the wave function describing collapsing dust in an anti-de Sitter background, as seen by a co-moving observer, by mapping the resulting variable mass Schrodinger equation to that of the quantum isotonic ...
Sandip Chowdhury +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Effect of Wetting and Drying Cycles on Swell/Collapse Behavior and Cracks of Fine – Grained Soils
Tikrit Journal of Engineering Sciences, 2011 Many of the soils undergo volumetric changes due to the change in the water content. Swell-shrink and collapse behavior of those soils affects the stress state in soil and the interacted structures.
Abdulrahman H. T. Al Zubaydi
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Suppression of Quantum-Mechanical Collapse in Bosonic Gases with Intrinsic Repulsion: A Brief Review
Condensed Matter, 2018 It is known that attractive potential ~− 1 / r 2 gives rise to the critical quantum collapse in the framework of the three-dimensional (3D) linear Schrödinger equation.
Boris A. Malomed
doaj +1 more source