Results 51 to 60 of about 5,144,321 (345)
Experimental Investigation of Column Separation Using Rapid Closure of an Upstream Valve
Applied Sciences, 2023 In this study, the phenomenon of column separation that occurs in the downstream pipeline of a rapid closure valve is experimentally investigated. Special attention is paid to the dynamic behavior of the formation, growth, and collapse processes of ...
Huan Wang, Ling Zhou, Deyou Liu
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
A chemo-mechanical coupling model of deviated borehole stability in hard brittle shale
Petroleum Exploration and Development, 2014 A chemo-mechanical coupling model of borehole stability in hard brittle shale considering structure characteristics and targeted hydration was established, the influencing factors of the distribution of collapse pressure were analyzed based on the model,
Hang WEN +6 more
doaj +1 more source
Cavitation bubble collapse pressures and erosion.
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1988 Cavitation damage was studied by both the measurements of cavitation bubble collapse pressures (impact loads) using our developed method with piezoelectric ceramics and the cavitation erosion tests of various metals in a magnetostrictive vibratory facility.
Yoshiro IWAI +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Vaidya Collapse with Nonzero Radial Pressure and Charge [PDF]
Axioms, 2020 The cosmic censorship hypothesis is regarded as one of the most important unsolved problems in classical general relativity; viz., will generic gravitational collapse of a star after it has exhausted its nuclear fuel lead to black holes only, under reasonable physical conditions.
openaire +2 more sources
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Frontiers in Mechanical EngineeringIt is essential to maintain the integrity of liner–cement–formation in the well completion and production stages. However, large liner deformations have been extensively experienced during hydraulic fracturing operations in carbonate formations.
Yanhui Han +3 more
doaj +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source