Results 101 to 110 of about 508,943 (271)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Blue-collar work and women's health: A systematic review of the evidence from 1990 to 2015

open access: yesSSM: Population Health, 2018
Despite the implications of gender and sex differences for health risks associated with blue-collar work, adverse health outcomes among blue-collar workers has been most frequently studied among men.
Holly Elser   +3 more
doaj   +1 more source

Loyalt\u27s Reward - A Felony Conviction: Recent Prosecutions of High-Status Female Offenders [PDF]

open access: yes, 2006
This Article analyzes white-collar female crime and compares several high profile cases to those of regular female offenders. It uses government statistical data on female crime to paint a portrait of the female offender.
Jacobs, Michelle S
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Impact of Crust Creation on Techno-Functional and Organoleptic Properties of Meat with Different Fat Contents

open access: yesApplied Sciences
In this study, the effects of crust formation were investigated on the quality properties of pork meat, including texture, colour, cooking loss, pH, water-holding capacity (WHC), and sensory attributes.
Tamás Csurka   +8 more
doaj   +1 more source

Direct Transient Analysis of a Fuze Assembly by Axisymmetric Solid Elements [PDF]

open access: yes, 1985
A fuze assembly, which consists of three major parts, nose, collar and sleeve, was designed to survive severe transverse impact giving a maximum base acceleration of 20.000 G. It is shown that hoop failure occurred in the collar after the impact.
Dai, C. C., Titus, J., Yang, J. C. S.
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

BLS Report On Labor Union And Employee Association Membership, 1973 [PDF]

open access: yes, 1979
Report about white collar employees belonging to unions and employee associations for the period 1976-1978.
Federal Employers of the Bay Area
core   +1 more source

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